Exam II ABX Drug-Bacteria Flashcards
What Bacteria types are natural Penicillins effective against?
Streptococcus
Enterococcus - VSE
HNM - N
Anaerobs - GP
What bacteria types are Aminopenicillins effective against?
Streptococcis
Enterococcus - VSE, and some VRE
Anaerobics - GP
What bacteria types are Penicillinase-resistant penicillins effective against?
Streptococcus
Staphylococcus - MSSA
Anaerobics - GP
What bacteria types are Antipseudomonal penicillins effective against?
Streptococcus
Staphylococcus - MSSA
HNM - N
Pseudomonas
Anaerobics - GP
What types of Bacteria are Beta-Lactamase/penicillin combos effective against?
(Often co-formulated with a drug that targets beta-lactamase)
Aminopenicillin / B-lactamase inh
Streptococcus
Enterococcus - VSE
GNR
HNM
Anaerobics
Antipseudomonal penicillin/B-lactamase inh
Streptococcus
Enterococcus - VSE
Staphylococcus - MSSA
GNR
HNM
Pseudomonas
Anaerobics
What Bacteria are 1st Generation Cephalosporins effective against?
Streptococcus
Staphylococcus - MSSA
GNR - few
What Bacteria are 2nd Generation Cephalosporins effective against?
Streptococcus
GNR
HNM
What Bacteria are 3rd Generation Cephalosporins effective against?
3rd Gen
Streptococcus
GNR
HNM
Ceftazidime
GNR
HNM
Pseudomonas
What Bacteria are 4th Generation Cephalosporins effective against?
Streptococcus
Staphylococcus - MSSA
GNR
HNM
Pseudomonas
What Bacteria are 5th Generation Cephalosporins effective against?
Streptococcus
Enterococcus - VSE
Staphylococcus - MSSA
GNR
HNM
What Bacteria are Cephalosporin/Beta-lactamase combos effective against?
Ceftazidime/Avibactam
GNR
HNM
Pseudomonas
Ceftolozane/Tazobactam
Streptococcus
GNR
HNM
Pseudomonas
What Bacteria are Carbapenems effective against?
(Should only be used for drug resistance, allergy, etc)
Ertapenem
Streptococcus
Enterococcus - VSE
Staphylococcus - MSSA
GNR
HNM
Anaerobics
Imipenm/Cilastatin
Meropenem
Doripenem
Streptococcus
Enterococcus - VSE
Staphylococcus - MSSA
GNR
HNM
Psuedomonas
Anaerobics
What bacteria are Carbapenem/Beta-lactamase INH effective against?
(Primarily used with carbapenem-resistant enterobacter)
Streptococcus
Enterococcus - VSE
Staphylococcus - MSSA
GNR
HNM
Psuedomonas
Anaerobics
What Bacteria is Monobactam effective against?
(Monobactam have no cross-reactivity with allergies to penicillins, cephalosporins, or carbapenems)
GNR
HNM
Pseudomonas
What Bacteria types are Glycopeptides effective against?
Streptococcus
VSE
MSSA
MRSA
GP+
What Bacteria are Tetracyclines used for?
ALL
Streptococcus
MSSA
MRSA
Doxycycline
HNM
Atypical
Minocycline
HNM
Tetracycline
HNM
Atypical
Tigecycline
VSE
GNR
HNM
Anaerobes
Omadacycline
VRE
GNR
+HM
Atypicals
Eravacycline
VRE
GNR
Anaerobes
What Bacteria are Fluoroquinolones effective against?
Ciprofloxacin
VSE
GNR
Pseudomonas
Levofloxacin
Streptococcis
VSE
GNR
HNM
Pseudomonas
Atypicals
Moxifloxacin
Streptococcis
GNR
HNM
Atypicals
Anaerobes
Ofloxacin
Streptococcis
MSSA
GNR
HNM
Pseudomonas
Delafloxacin
Streptococcis
MSSA
MRSA
GNR
HNM
Pseudomonas
Atypicals
What bacteria are Macrolides effective against?
Streptococcus
H+
Atypicals
What bacteria are Clindamycin effective against?
Streptococcus
MSSA
GP+ (Anaerobes)
What bacteria is Metronidazole effective against?
Anaerobes
What Bacteria is Bactrim effective against?
Streptococcus
MSSA
MRSA
GNR
HNM
What bacteria are Aminoglycosides effective against?
Solo
GNR
Pseudomonas
For Synergy
Streptococcis
VSE
VRE
MSSA
MRSA
What bacteria is Nitrofurantoin effective against?
VSE
GNR
What bacteria are Oxazolidinones effective against?
Streptococcis
VSE
VER
MSSA
MRSA
GP+
What bacteria is Daptomycin effective against?
Streptococcus
VSE
VRE
MSSA
MRSA
What Bacteria are streptogramins effective against?
VSE
VRE
MSSA
MRSA
What Bacteria is Rifampin effective against?
MSSA
MRSA
What Bacteria is Fosfomycin effective against?
VSE
VRE
MSSA
MRSA
GNR
Pseudomonas
What bacteria is Fidaxomycin effective against?
C Diff