McLaughlin- New Approach Flashcards

1
Q

What is target of MTI-101? What is its unique mechanism of action?

A

Multiple Myeloma cells (plasma) in bone marrow. It is the only drug that induces necrosis, not autophagy or apoptosis. Binds to CD44 inhibiting it, mimicing fibronectin.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What type of molecule is MTI-101?

A

Cyclic peptoid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly