McLaughlin- New Approach Flashcards
1
Q
What is target of MTI-101? What is its unique mechanism of action?
A
Multiple Myeloma cells (plasma) in bone marrow. It is the only drug that induces necrosis, not autophagy or apoptosis. Binds to CD44 inhibiting it, mimicing fibronectin.
2
Q
What type of molecule is MTI-101?
A
Cyclic peptoid