May-Connective Tissue Flashcards
what type of connective tissue is found in gelatinous ground substance?
connective tissue proper
what type of connective tissue consists of cells and fibers embedded in a solid ground substance?
supportive connective tissue
what types of connective tissue proper are there?
loose and dense
what types of supportive connective tissue are there?
cartilage and bone
name all types of loose connective tissue.
areolar, adipose, reticular, hemopoietic
what type of connective tissue can be regularly or irregularly arranged?
dense connective tissue
how are tendons and ligaments typically arranged?
arranged regularly
is collagen acidophillic?
yes
what amino acids make up collagen?
glycine (33%), proline (12%) and hydroxyproline (10%)
what is the monomer of collagen?
tropocollagen
protocollagen consists of 3 helically arranged polypeptide chains. what holds it together?
hydrogen bonds: 3 total
2 are alpha-1
1 is alpha-2
where does synthesis of collagen occur?
in the cisternae of the rough ER
where are glycoproteins added to protocollagen?
in the Golgi
what acts as a coenzyme for procollagen hydroxylase?
ascorbic acid (Vitamin C)
what is the purpose of procollagen peptidase?
to convert procollagen to tropocollagen
what is the purpose of lysyl oxidase?
catalyzes the cross links between tropocollagen molecules to form mircrofibrils
what is the most common type of collagen?
Type 1
example of type 2 collagen?
cartilage
example of type 3 collagen?
smooth muscle, aa, uterus, spleen, lungs
example of type 4 collagen?
basal laminas
example of type 5 collagen?
placental membranes
elastic fibers contains an amorphous compontent and a microfibril component, what are they?
elastin (amorphous) and fibrillin (microfibril)
how is elastin similar to collagen?
both rich in glycine and proline
what type of collagen are reticular fibers composed of?
type 3
where are reticular fibers abundant?
at boundaries between connective tissue and other tissues.
what form the majority of stroma in meloid and lymphoid tissues?
reticular fibers
since reticular fibers are argyophilic what does that mean?
blacken with silver stains
what two fibers exhibit the same 64 nm periodicity?
collagen and reticular fibers
what are examples of ground substance?
glycoproteins, glycosaminoglycans (GAG) and proteogylcans
what type of GAG lacks a sulfate group and is mainly viscous?
hyaluronic acid
what type of GAG is sulfated and present in hard connective tissues?
chondroitin