May-Connective Tissue Flashcards

1
Q

what type of connective tissue is found in gelatinous ground substance?

A

connective tissue proper

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2
Q

what type of connective tissue consists of cells and fibers embedded in a solid ground substance?

A

supportive connective tissue

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3
Q

what types of connective tissue proper are there?

A

loose and dense

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4
Q

what types of supportive connective tissue are there?

A

cartilage and bone

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5
Q

name all types of loose connective tissue.

A

areolar, adipose, reticular, hemopoietic

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6
Q

what type of connective tissue can be regularly or irregularly arranged?

A

dense connective tissue

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7
Q

how are tendons and ligaments typically arranged?

A

arranged regularly

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8
Q

is collagen acidophillic?

A

yes

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9
Q

what amino acids make up collagen?

A

glycine (33%), proline (12%) and hydroxyproline (10%)

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10
Q

what is the monomer of collagen?

A

tropocollagen

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11
Q

protocollagen consists of 3 helically arranged polypeptide chains. what holds it together?

A

hydrogen bonds: 3 total
2 are alpha-1
1 is alpha-2

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12
Q

where does synthesis of collagen occur?

A

in the cisternae of the rough ER

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13
Q

where are glycoproteins added to protocollagen?

A

in the Golgi

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14
Q

what acts as a coenzyme for procollagen hydroxylase?

A

ascorbic acid (Vitamin C)

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15
Q

what is the purpose of procollagen peptidase?

A

to convert procollagen to tropocollagen

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16
Q

what is the purpose of lysyl oxidase?

A

catalyzes the cross links between tropocollagen molecules to form mircrofibrils

17
Q

what is the most common type of collagen?

A

Type 1

18
Q

example of type 2 collagen?

A

cartilage

19
Q

example of type 3 collagen?

A

smooth muscle, aa, uterus, spleen, lungs

20
Q

example of type 4 collagen?

A

basal laminas

21
Q

example of type 5 collagen?

A

placental membranes

22
Q

elastic fibers contains an amorphous compontent and a microfibril component, what are they?

A

elastin (amorphous) and fibrillin (microfibril)

23
Q

how is elastin similar to collagen?

A

both rich in glycine and proline

24
Q

what type of collagen are reticular fibers composed of?

A

type 3

25
Q

where are reticular fibers abundant?

A

at boundaries between connective tissue and other tissues.

26
Q

what form the majority of stroma in meloid and lymphoid tissues?

A

reticular fibers

27
Q

since reticular fibers are argyophilic what does that mean?

A

blacken with silver stains

28
Q

what two fibers exhibit the same 64 nm periodicity?

A

collagen and reticular fibers

29
Q

what are examples of ground substance?

A

glycoproteins, glycosaminoglycans (GAG) and proteogylcans

30
Q

what type of GAG lacks a sulfate group and is mainly viscous?

A

hyaluronic acid

31
Q

what type of GAG is sulfated and present in hard connective tissues?

A

chondroitin