Kuehn - fetal period and developmental abnormalities Flashcards

1
Q

what is the umbilical vesicle “yolk sac”

A

early nutrient transfer to developing embryo, formation of germinal cells, and earliest site of blood cell development

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2
Q

what is the amniotic membrane

A

contains the amniotic fluid

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3
Q

where does the amniotic fluid come from

A

placenta, amniotic membrane, embryonic urine, and guts

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4
Q

what is the function of the amniotic fluid

A

protects from injury, prevents fetal/amnion fusion, permits symmetrical growth of NBI limbs, regulates temperature and fluid exchange

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5
Q

what is the term for when amniotic fluids are too low

A

oligohydramnios

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6
Q

what are the consequences of oligohydramnios

A

poor renal function in fetus, club foot/club hands or hypolasmic lungs (too small to function after birth)

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7
Q

what is polyhydramnios

A

too much amniotic fluid

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8
Q

what are the consequences of polyhydramnios

A

esophageal atresia, cord prolapse and placental abruption

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9
Q

what is the chorion

A

space between amnion and uterus - filled with fluid early in life and will disappear

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10
Q

what are the chorionic villi for

A

increase surface area - collect nutrients from maternal blood

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11
Q

what separates the pleural and pericardial cavities

A

pleuropericardial membrane

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12
Q

what does the pleuropericardial membrane become after it closes as a hole

A

pleuropericardial canal

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13
Q

what does the pleruoperitoneal membrane incorporate into

A

the diaphragm

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14
Q

what happens with congenital diaphragmatic herniation

A

left pleuroperitoneal membrane fails to complete its attachments and structures in left upper abdomen will herniate into left pleural cavity (lung on that side will fail to grow)

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15
Q

at what weight is a premature birth viable

A

more than 500 grams (1 lb)

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16
Q

what are 2 ways to determine age of fetus

A

LMP (LNMP- last normal menstrual period) or estimated day of fertility = LMP - 2 weeks

17
Q

how long is a trimester

A

about 13 weeks

18
Q

what happens in the 1st trimester

A

most critical part of development

19
Q

what trimester can a fetus survive outside the womb

A

3rd trimester

20
Q

what is the difference between previable and viable

A

previable = the fetus’ lungs aren’t fully developed and cannot survive outside womb, viable = developed enough to survive

21
Q

when can you first feel fetal movements

A

17-20 weeks

22
Q

what is a dizygotic (fraternal) twin

A

2 seperate oocytes fertilized independently = 2 seperate fetus

23
Q

what is a monozygotic (identical) twin

A

1 zygote or blastocyte divides = 2 embryos with same DNA

24
Q

what is the safest procedure for testing for defects

A

ultrasound - high frequency sounds bounce off fetus

25
when would you use amniocentisis testing and what does it do
after age 35 - at 15-20 weeks (early 11-13 weeks) sample amniotic fluid and cells - keryotyping or biochemical tests
26
what does a chronic villus sample (CVS) do and when would you do it
collects chorionic villus cells for karyotyping - at 10-12 weeks
27
what is the fetoscopy test and when is it used
endoscope in amnion - used in unusual circumstances (twin-twin transfusion)
28
what 2 tests are hazardous to an early fetus (can be used late 3rd trimester)
X-ray and CT scan
29
when are defects so severe the result is death
1st 2 weeks
30
what time period are defects organogenesis and have serious malformations
weeks 3-8
31
what is a cleft
failure of fusion
32
what is agenisis
failure of an organ to develop
33
what is ectopy
abnormal location of development
34
what is stenosis
abnormal narrowing
35
what is a fistula
abnormal connection
36
what is a cyst
abnormal fluid-containing structure
37
what is atresia
a blind tube