Maturation of Erythrocytes Flashcards
First stage of Maturation of Erythrocytes
Proerythroblast
About 20qm in size
Large spherical nucleus with several visible nucleoli
Finely granular chromatin structure
Basophilic cytoplasm caused by Polyribosomesw
Second stage of Maturation of Erythrocytes
Basophilic Erythroblast
10-16qm in size
spherical nucleus but no visible nucleoli
Basophilic cytoplasm caused by Polyribosomes
Third stage of Maturation of Erythrocytes
Polychromatophilic Erythroblast 10-12qm in size smaller nucleus but no visible nucleoli condensed chromatin (clock-face like) Basophilia and Eosinophilia can be observed which is effectively caused by the remaining Polyribosomes and the hemoglobin which is produced by rER and Golgi-Complex
Fourth stage of Maturation of Erythrocytes
Orthochromatophilic Erythroblast
8-10qm in size
small nucleus with with highly condensed chromatin
nucleus is extruded at the end of this stage.
it has abundant eosinophilic cytoplasm caused by the haemeglobin earlier produced by the golgi complex and the rER
Fifth stage of Maturation of Erythrocytes
Reticulocyte
-anucleate
size about that of an erythrocyte (7.5qm, 2.6qm thickatrim, 0.8qm thick in centre)
have a netlike structure in their cytoplasm when dyed with brilliant cresyl blue they are the remaining ribosomes.
Sixth stage of Maturation of Erythrocytes
Erythrocyte -anucleate size: 7.5qm thickness: 2.6qm at rim, 0.8qm thick in centre biconcave shape which
Erythrocytes
- 5 - 6.0 Million /qL of blood in Males
- 0 - 5.2 Million /qL of blood in Females
It is quite flexible a property that permits to adapt to the irregular shapes and small diameters of capillaries.
Surrounded by Plasmalemma
Plasmalemma of Erythrocyte
is another name for the plasma membrane of an Erythrocyte
It consists of about 40% lipids (phospholipids, glycolipids, cholesterol)
50% Proteins and 10% Carbohydrates.
Half of the Proteins span the lipid bilayer and are known as integral proteins.
