Granulopoiesis (Maturation of Granulocytes)

Question 1

Leukogramm

Answer 1

4.000-10.000 /qL (Microliter)
Percentage of each individual type of Leukocyte (Leuko=white cyte=cell)

(Never Let Monkeys Eat Bananas)
Neutrophils 60-70% (2-5% are band or rod-like forms)
Lymphocytes 20-40%
Monocytes 2-10%
Eosinophils 2-5%
Basophils 0-1%

Question 2

First stage of Granulopoiesis

Answer 2

Myeloblast
Size 15-20qm
Large nucleus, finely granular chromatin structure, several nucleoli, strong basophillia
paranuclear lightening at the locality of the cytocentrum

Question 3

Second stage (1st part) of Granulopoiesis

Answer 3

Promyelocyte I (early stage)
22-25 µm
azurophilic granules produced by rER and golgi c. (contain lysosomes)
Developed golgi complex

Question 4

Second stage (2nd part) of Granulopoiesis

Answer 4

Promyelocyte II (late stage)
about the same size 22-25qm
azurophilic granules (lysosomes)
develops first specific granules (neutrophilic, eosinophilic, basophilic)
developed golgi complex

Question 5

Third stage of Granulopoiesis

Answer 5

Myelocyte (Eosinophilic, Basophilic, Neutrophilic)
15-20qm in size
oval nucleus, coarser chromatin clumps
developed golgi complex producing granules

Question 6

Fourth stage of Granulopoiesis

Answer 6

Metamyelocyte
hourse-shoe nucleus
post-mitotic