Matthys: Intro to Dermatology Flashcards

1
Q

Macule

A

-Flat spot on skin measuring <1cm

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2
Q

Patch

A

> 1 cm

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3
Q

Papule

A

-nonpustular, nonvesicular lesion on skin <1 cm

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4
Q

Nodule

A

> 1cm

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5
Q

Vesicle

A

-small blisters <1 cm

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6
Q

Bulla

A

> 1 cm

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7
Q

Pustule

A

-a collection of leukocytes in the epidermis

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8
Q

Plaque

A

-broad, elevated flat lesions > 1cm

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9
Q

If there is an erythematous lesion that is non scaling, what could it be?

A
  • if localized with sepsis: cellulitis
  • localized w/o sepsis: insect bites, acne, hemangioma
  • generalized systemic signs: urticaria, EN, Viral exanthems, annular erythemas
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10
Q

If there is an erythematous lesion that is scaling, what could it be?

A
  • if papulosquamous: pityriasis, psoriasis, tinea corporis, syphillis…
  • if eczematous: atopic dermatitis, contact dermatitis, scabies…
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11
Q

clinical findings of atopic dermatitis

A
  • Xerosis and icthyosis vulgaris
  • pigmentary changes
  • eye and periorbital changes
  • hand and foot dermatitis (allergic salute)
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12
Q

differential dx with atopic dermatitis

A
  • allergic contact dermatitis
  • seborrheic dermatitis
  • tinea infection
  • nummular eczema
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13
Q

tx for atopic dermatitis

A
  • moisturize
  • avoid irritants
  • avoid known food allergies
  • topical and oral antipruritic agents
  • anti-inflammatory agents
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14
Q

cellulitis

A
  • acute, rapidly spreading nonsupprative infection of the skin and underlying soft tissue NOT including the muscle
  • Erysipelas is more superficial than cellulitis
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15
Q

clinical findings in cellulitis

A
  • tender, warm, poorly demarcated boggy plaque
  • commonly on an extremity
  • trauma
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16
Q

pathogenesis of cellulitis

A
  • trauma to an extremity either known or unknown

- concurrent ulcer

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17
Q

Risk factors for cellulitis

A
  • stasis dermatitis

- lymphedema

18
Q

ddx for cellulitis

A
  • venous thrombosis
  • gout
  • lipodermatosclerosis
  • chronic stasis dermatitis
19
Q

Tx for cellulitis

A
  • becuase it’s usually due to staph aureus or strep pyogenes, just use first gen cephalosporin, macrolide, or clindamycin
  • elevation
20
Q

Erythema nodosum

A
  • 20-30

- symmetric erythematous nodules and plaques located on the anterior lower extremities

21
Q

clinical findings for EN

A
  • tender nodules and plaques on the bilateral knees, ankles, and shins
  • sometimes thighs and upper extremity
  • one to 15 cm in size
  • rarely ulcerate
22
Q

what causes EN?

A
  • hypersensitivity things
  • he said birth control was a big one
  • septal panniculitis is ddx
  • sarcoidosis
23
Q

tx for EN

A

-anti inflammatory and rest

24
Q

What is the koebner phenomenon?

A

-re create psoriasis by trauma… not contagious

25
What is the auspitz sign?
-peel away the psoriatic scale and get pinpoint bleeding
26
What is Woronoff's ring?
-when you get rid of psoriasis and it leaves behind a pigmented ring
27
different types of psoriasis?
- plaque type - pustular - Guttate
28
Plaque type psoriasis
- well demarcated scaly plaque - elbows, knees, belly button - coin shaped - annular pattern - thick
29
Histology of psoriasis
- acanthotic epidermis with club shaped rete ridges and an absent granular layer - tortuous vessels seen in the papillary dermis
30
ddx for psoriasis
- seborrheic dermatitis | - nummular eczema
31
if there is a coin shaped lesion with a thin plaque, what is that?
-nummular eczema
32
pustular psoriasis
- sterile sheets of pustules on an erythematous base - localized or generalized - painful with fever - guy who looked like he had a shit ton of zits
33
ddx for pustular psoriasis
- AGEP - Drug eruption - Subcorneal pustular dermatosis
34
Guttate
- children and young adults - post strep infection - some predisposition to psoriasis - trunk with sparing of palms and soles
35
guttate ddx
- secondary syphillis (contagious) | - pityriasis rosea
36
Herpes Zoster
- reactivated varicella zoster virus | - immunocompromised
37
clinical findings for herpes zoster
- local radicular pain 2-3 days prior to the eruption - disseminated zoster - herpes zoster ophthalmicus - postherpetic neuralgia
38
what will we see on pathology for herpes zoster?
- steel gray nuclei | - multinucleated giant cells with eosinophilic intranuclear inclusions
39
ddx of herpes zoster
- chicken pox - atypical measles - cellulitis
40
Tx for Herpes Zoster
- antivirals - contagious; can cause chickenpox - pain control - vaccine at age 60