Matthys: Intro to Dermatology Flashcards

1
Q

Macule

A

-Flat spot on skin measuring <1cm

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2
Q

Patch

A

> 1 cm

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3
Q

Papule

A

-nonpustular, nonvesicular lesion on skin <1 cm

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4
Q

Nodule

A

> 1cm

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5
Q

Vesicle

A

-small blisters <1 cm

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6
Q

Bulla

A

> 1 cm

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7
Q

Pustule

A

-a collection of leukocytes in the epidermis

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8
Q

Plaque

A

-broad, elevated flat lesions > 1cm

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9
Q

If there is an erythematous lesion that is non scaling, what could it be?

A
  • if localized with sepsis: cellulitis
  • localized w/o sepsis: insect bites, acne, hemangioma
  • generalized systemic signs: urticaria, EN, Viral exanthems, annular erythemas
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10
Q

If there is an erythematous lesion that is scaling, what could it be?

A
  • if papulosquamous: pityriasis, psoriasis, tinea corporis, syphillis…
  • if eczematous: atopic dermatitis, contact dermatitis, scabies…
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11
Q

clinical findings of atopic dermatitis

A
  • Xerosis and icthyosis vulgaris
  • pigmentary changes
  • eye and periorbital changes
  • hand and foot dermatitis (allergic salute)
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12
Q

differential dx with atopic dermatitis

A
  • allergic contact dermatitis
  • seborrheic dermatitis
  • tinea infection
  • nummular eczema
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13
Q

tx for atopic dermatitis

A
  • moisturize
  • avoid irritants
  • avoid known food allergies
  • topical and oral antipruritic agents
  • anti-inflammatory agents
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14
Q

cellulitis

A
  • acute, rapidly spreading nonsupprative infection of the skin and underlying soft tissue NOT including the muscle
  • Erysipelas is more superficial than cellulitis
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15
Q

clinical findings in cellulitis

A
  • tender, warm, poorly demarcated boggy plaque
  • commonly on an extremity
  • trauma
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16
Q

pathogenesis of cellulitis

A
  • trauma to an extremity either known or unknown

- concurrent ulcer

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17
Q

Risk factors for cellulitis

A
  • stasis dermatitis

- lymphedema

18
Q

ddx for cellulitis

A
  • venous thrombosis
  • gout
  • lipodermatosclerosis
  • chronic stasis dermatitis
19
Q

Tx for cellulitis

A
  • becuase it’s usually due to staph aureus or strep pyogenes, just use first gen cephalosporin, macrolide, or clindamycin
  • elevation
20
Q

Erythema nodosum

A
  • 20-30

- symmetric erythematous nodules and plaques located on the anterior lower extremities

21
Q

clinical findings for EN

A
  • tender nodules and plaques on the bilateral knees, ankles, and shins
  • sometimes thighs and upper extremity
  • one to 15 cm in size
  • rarely ulcerate
22
Q

what causes EN?

A
  • hypersensitivity things
  • he said birth control was a big one
  • septal panniculitis is ddx
  • sarcoidosis
23
Q

tx for EN

A

-anti inflammatory and rest

24
Q

What is the koebner phenomenon?

A

-re create psoriasis by trauma… not contagious

25
Q

What is the auspitz sign?

A

-peel away the psoriatic scale and get pinpoint bleeding

26
Q

What is Woronoff’s ring?

A

-when you get rid of psoriasis and it leaves behind a pigmented ring

27
Q

different types of psoriasis?

A
  • plaque type
  • pustular
  • Guttate
28
Q

Plaque type psoriasis

A
  • well demarcated scaly plaque
  • elbows, knees, belly button
  • coin shaped
  • annular pattern
  • thick
29
Q

Histology of psoriasis

A
  • acanthotic epidermis with club shaped rete ridges and an absent granular layer
  • tortuous vessels seen in the papillary dermis
30
Q

ddx for psoriasis

A
  • seborrheic dermatitis

- nummular eczema

31
Q

if there is a coin shaped lesion with a thin plaque, what is that?

A

-nummular eczema

32
Q

pustular psoriasis

A
  • sterile sheets of pustules on an erythematous base
  • localized or generalized
  • painful with fever
  • guy who looked like he had a shit ton of zits
33
Q

ddx for pustular psoriasis

A
  • AGEP
  • Drug eruption
  • Subcorneal pustular dermatosis
34
Q

Guttate

A
  • children and young adults
  • post strep infection
  • some predisposition to psoriasis
  • trunk with sparing of palms and soles
35
Q

guttate ddx

A
  • secondary syphillis (contagious)

- pityriasis rosea

36
Q

Herpes Zoster

A
  • reactivated varicella zoster virus

- immunocompromised

37
Q

clinical findings for herpes zoster

A
  • local radicular pain 2-3 days prior to the eruption
  • disseminated zoster
  • herpes zoster ophthalmicus
  • postherpetic neuralgia
38
Q

what will we see on pathology for herpes zoster?

A
  • steel gray nuclei

- multinucleated giant cells with eosinophilic intranuclear inclusions

39
Q

ddx of herpes zoster

A
  • chicken pox
  • atypical measles
  • cellulitis
40
Q

Tx for Herpes Zoster

A
  • antivirals
  • contagious; can cause chickenpox
  • pain control
  • vaccine at age 60