Maternal CNS Changes Flashcards

1
Q

MAC progressively decreases during pregnancy due to:

A

Hormonal (progesterone) changes

increased level of Beta-endorphin

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2
Q

_______sensitivity to LA, therefore reduce dose up to ___%

A

Increase, 30%

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3
Q

Obstruction of IVC by gravid uterus causes:

A
  1. Distension of epidural venous plexus
  2. Increase epidural blood volume
    - decreased spinal CSF volume
    -decreased potential volume of epidural space
    (these will increase cephalad spread of LA during spinal and epidural anesthesia.)
    -increased epidural pressure.
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