Maternal adaptation Flashcards
Softening of the uterine isthmus during 8 weeks AOG:
a. Chadwick’s Sign
b. Goodell sign
c. Hegar Sign
d. Cullen Sign
C
During pregnancy the uterus increases in size. This is not normally due to:
a. Increase in volume of uterine content
b. Some increase in numbers of muscle cells
c. Muscle cell hypertrophy
d. Growth of intrauterine fibroids
D
Braxton Hick’s Contraction is not:
a. Palpable
b. Painless
c. Irregular
d. Purposeful
D
Softening of the cervix that occurs early in pregnancy
a. Hegar’s Sign
b. Cullen’s Sign
c. Goodell’s Sign
d. Hick’s Sign
C
Chadwick’s sign of pregnancy is:
a. Softening of the isthmus uteri
b. Bluish discolouration of cervix and vagina
c. An enlargement of the fundus of the uterus
d. An irregularity of the uterine fundus during pregnancy
B
Pregnant uterus has the following characteristics:
a. Contracts only at the onset of labor
b. Can markedly enlarge and return to normal size
c. Has the most marked growth in the lower uterine segment
d. Both A and C
B
Anemia for both mother and fetus is most commonly found in the following EXCEPT:
a. Early Pregnancy
b. Patients of high parity
c. Young gravidas
d. Inadequate prenatal care
A
Large uterine blood vessels from pregnancy normally undergo changes post partum. These changes include all, EXCEPT:
a. Thrombosis
b. Slow Reabsorption
c. Hyalinization
d. Calcification
D
Normal ovarian changes during pregnancy incude:
a. Luteoma
b. Decidual reaction on the surface
c. Corpus Luteum of pregnancy
d. AOTA
D
The corpus luteum of pregnancy functions maximally during
a. 4-5 weeks AOG
b. 5-6 weeks AOG
c. 6-7 weeks AOG
d. 7-8 weeks AOG
C
Which of the following coagulation factors remain unchanged during pregnancy?
a. Clotting time
b. D-dimer concentration
c. Plasma Fibrinogen levels
d. Platelet count
A
The following increases are noted in pregnancy EXCEPT:
a. Erythropoietin levels
b. Hemoglobin and hematocrit
c. Plasma and RBCs
d. Reticulocyte count
B
Pregnancy induced hypervolemia serves to
a. Protect the mother against blood loss during parturition
b. Meet the demands of the enlarged uterus with its greatly hypertrophied vascular system
c. Protects the mother and fetus against the effects of impaired venous return in supine and erect positions
d. AOTA
D
“Accelerated starvation” in pregnancy pertains to:
a. increased lipolysis with liberation of free fatty acids as a result of placental lactogen production
b. pregnancy-induced switch in fuels from glucose to lipids during the fasting state
c. progesterone and estrogen mediated peripheral insulin
resistance
d. prolonged hyperglycemia and hyperinsulinemia with greater suppression of glucagons after a meal
B
Relaxin is secreted by the following organs EXCEPT:
a. Corpus luteum
b. Heart
c. Myometrium
d. Placenta
C
Theca lutein cyst are benign ovarian lesions seen in which of the following:
a. Pregnancy
b. Hyperthyroidism
c. Gestational trophoblastic diseases
d. AOTA
D
The following are effects of hyperestrogenemia EXCEPT:
a. Vascular spiders
b. Palmar erythema
c. Hyperreactio luteinalis
d. Chloasma
C
Which of the following minerals remain unchanged during pregnancy?
a. Phosphate
b. Magnesium
c. Iron
d. Calcium
A
Which of the following are true regarding serum Na and K levels in pregnancy EXCEPT:
a. Increase in the renal secretion rate of Na and K
b. Increased in Glomerular filtration rate of Na and K
c. Enhanced tubular reabsorption of Na and K
d. NOTA
A
The total iron requirement during pregnancy is:
a. 500 mg
b. 1000 mg
c. 1500 mg
d. 2000 mg
B
Which of the following is true regarding the peptide hormone leptin?
a. May be related to preeclampsia and fetal growth restriction
b. Increase in pregnancy is due to maternal weight gain and placental weight
c. Primarily secreted by adipose tissue
d. AOTA
D
The major storage depots that are intimately involved with the storage hormone insulin in the metabolism of nutrients absorbed from the maternal gut are:
a. Adipose tissue
b. Liver
c. Muscle
d. AOTA
D
Mechanism that explain the occurrence of pyrosis, except
a. Lower esophageal sphincter tone
b. Higher intragastric pressure
c. Lower intraesophageal pressure
d. Lower wave speed & higher amplitude of esophageal peristalsis
D
Liver changes during pregnancy include:
a. Decreased hepatic flow and diameter of portal vein
b. Total albumin is decreased
c. Serum albumin concentration is decreased
d. AST, ALT, bilirubin levels are increased
C
The liver enzyme has oxytocinase and vasopressinase activity
a. Serum aspartate transaminase
b. Leucine aminopeptidase
c. Alanine Transminase
d. Gamma Glutamyl transferase
B
Which hormone impairs gallbladder contraction during pregnancy by inhibiting Cystokinin-mediated smooth muscle stimulation:
a. Aldosterone
b. Testosterone
c. Estrogen
d. Progesterone
D
High levels of this hormone during pregnancy inhibit intraductal transport of bile and this cause intrahepatic cholestasis
a. Estrogen
b. Progesterone
c. Aldosterone
d. Testosterone
A
The following statements is true about GH during pregnancy:
a. GH is secreted only by the maternal pituitary gland
b. GH peaks in the amniotic fluid at 17 weeks AOG
c. The placenta is the principle source of GH secretion beginning 8 weeks AOG
d. Maternal Levels of GH slowly increase and plateau at 28 weeks AOG
D
Increased Prolactin secretion is brought about by:
a. TSH
b. Serotonin
c. Dopamine
d. Progesterone
B
There are a number of alterations in thyroid physiology and function during pregnancy, which includes:
a. Increased TRH
b. Decreased total serum thyroxine
c. Increased TBG
d. Decreased Total T3
C
____ is structurally similar to TSH and hence has intrinsic thyrotropic activity
a. hCG
b. TRH
c. Total T3
d. Total Thyroxine
A
The following facilitate the conversion of Vit D to 1,25 dihydroxyvitamin D3, except
a. Increased Parathyroid hormone
b. Increased Calcitonin
c. Decreased Calcium
d. Decreased phosphate
B
True of thyroid physiology during pregnancy
a. The complex alterations of thyroid regulation alters maternal thyroid status as measured by metabolic studies
b. The basal metabolic rate remains unchanged throughout gestation
c. If fetal body surface is considered along with that of the mother, then the basal metabolic rates are similar to those in nonpregnant women
d. Normal suppression of TSH may lead to a misdiagnosis of subclinical hypothyroidism
D
Increased levels of parathyroid hormone during pregnancy result from:
a. Increased calcium concentration in pregnant women
b. Decreased plasma volume
c. Decreased glomerular filtration rate
d. Materno-fetal transfer of calcium
D
Causes of elevated aldosterone secretion during pregnancy include:
a. Decreased Renin
b. Decreased Sodium intake
c. Decreased Angiotensin II
d. Increased Fetal Gland Secretion
B
The following statements are true about maternal androgens during pregnancy EXCEPT:
a. Maternal androstenedione and testosterone production are increased
b. Maternal androstenedione is converted to estradiol
c. Increased SHBG decreases maternal testosterone
d. Little or no testosterone in maternal plasma enters the fetal circulation
C
Which of the following is decreased in pregnancy
a. CO
b. Stroke Volume
c. Systemic Vascular resistance
d. Heart Rate
C
In which AOG would you except the greatest risk of decompensation in a gravidocardiac?
a. 5-10 weeks
b. 24-28 weeks
c. During labor
d. Immediately postpartum
D
Which of the following is the product of systemic vascular resistance and Heart rate?
a. Stroke Volume
b. Cardiac Output
c. Blood Pressure
d. Ejection Friction
B
How would you advise a pregnant woman who complains of feeling faint after lying flat on bed?
a. Move slowly to wait for her BP to stabilize
b. Use a higher pillow
c. Elevate her legs when sleeping
d. Sleep or relax on her left side
D
A patient is taking Metoprolol for mild hypertension prior to pregnancy. Which of the following is true in her case?
a. She may not need anti-hypertensives in the most parts of her pregnancy
b. She would have to be maintained in the same dose of her anti-hypertensives
c. She would have to increase the dose of her anti-hypertensive medications
d. Her hypertension would behave erratically during pregnancy
A
Which of the following stays the same during pregnancy?
a. Vital Capacity
b. Total lung Capacity
c. Tidal Volume
d. Inspiratory Capacity
B
The following is the result of the elevated diaphragm in pregnancy
a. Increased functional residual capacity
b. Decreased residual volume
c. Increased respiratory rate
d. Decreased alveolar ventilation
B
Mild dilatation of the renal pelvis in pregnancy is due to
a. Elevation of estrogen
b. Elevation of the diaphragm
c. Elevation of progesterone
d. Elevation of the cardiac output
C
The bipedal edema and varicose veins in pregnancy may result from
a. The compression of the iliac veins by the fetal head
b. Increase in the risk of venous thromboembolism
c. Supine hypotension syndrome
d. Patency of the venous valves
A
Which cardiac examination finding in pregnancy is most INCOMPATIBLE with normal:
a. Split S1
b. Systolic murmur
c. Diastolic Murmur
d. Mildly thicker left ventricle
C
Higher progesterone in pregnancy results in the following change in the urinary system
a. Higher creatinine clearance
b. More residual urine
c. Higher glomerular filtration rate
d. Lower risk for ascending urinary infection
B
Which of the following diseases may be masked by the physiologic changes in pregnancy?
a. Kidney disease
b. Cardiac disease
c. Pulmonary Disease
d. Deep Vein Thrombosis
A
The hyperpigmentation associated with pregnancy is presumed to be due to increased levels of which hormone
a. TSH
b. MSH
c. GnRH
d. SRH
B
A 25 year old primigravid comes to the OPD Clinic with the following dermatologic manifestation, a diffuse hyperpigmentation on the face. What is your diagnosis?
a. Striae Gravidarum
b. Linea Nigra
c. Melasma Gravidarum
d. Chloasma Gravidarum
C
Development of new nevi during pregnancy is thought to be an effect of
a. Increased estrogen deposition
b. Increased progesterone deposition
c. Increased MSH deposition
d. Increased melanin deposition
D
Your 31 y/o patient who is into her 34th weeks of pregnancy complains of diffuse mottling of her palms. This condition is through to be due to several contributory factors. Which of the following is NOT
contributory to this condition?
a. Hormone Replacement Therapy
b. Hypokinetic circulation
c. Increased estrogen levels
d. Genetic predisposition
A
What is the major contributory factor to the development of hemorrhoids during pregnancy?
a. Hyperestrogenic state
b. Increased blood volume during pregnancy
c. Prolonged standing
d. Increased weight of the gravid uterus
D
True statements about hyperpigmentation during pregnancy
A. Skin darkening develops in 10%
B. Pigmentation is more pronounced in women with white complexion
C.Dermal melanosis may persist up to 10 years in a third of affected women
D. Results from elevated MSH
D
True about hyperpigmentation EXCEPT
A. More pronounced in the areola, perineum, umbilicus and axilla
B. Begins to be evident usually in the 3rd trimester
C. Affects recent scars
D. Regresses postpartum
B
True statements about striae gravidarum EXCEPT
A. Family history is the strongest factor
B. These are silvery lines that represent the remains of previous striae in multigravids
C. Majority develop in the abdomen but may also be seen in the breast and thighs
D. Topical application of lotion during the first trimester will prevent this
D
True statements about nevi during pregnancy EXCEPT
A. A small minority develop enlarged melanocytes and increased melanin deposition
B. It is common for nevi to increase in diameter or become darker
C. No proof of malignant transformation
D. Further examination of nevi [which] enlarge
B
Mrs Martinez consulted with excessive hair loss. She delivered by CS two months ago. What will you advise her?
A. Will grow back in 2 months
B. There’s no treatment required
C. Further investigation
B
True statements about hirsutism during pregnancy EXCEPT
A. Mild hirsutism is common
B. Women with predisposed genetically to coarse hair growth are more severely affected
C. Typically persists within several months after delivery
D. Prompt investigation if with other evidence of masculinization
C
Starting at 12 weeks of age, changes in uterine size are predominantly due to
a. Pressure from products of conception
b. Stimulation of estrogen
c. Initial position of placenta
d. Increasing production of myocytes
A