Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Step 3 > Master the Boards: Rheumatology 4 > Flashcards

Master the Boards: Rheumatology 4 Flashcards

1
Q

Complex regional pain syndrome features 4

A
  • severe excruciating pain in limb with allodynia
  • vasomotor sx w intermittent edema skin color changes
  • previous hx of trauma damaging myelin or peripheral nerves
  • nuclear bone scan/MRI can be abnormal
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Complex regional pain syndrome tx

A

NSAIDS, TCA’s, gabapentin/pregabalin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

5 common clinical features of all vasculitis types

A
  • fatigue/malasie/weight loss
  • Fever
  • palpable purpura/rash
  • neuropathy
  • joint pain
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

3 common lab findings all vasculitis

A
  • normocytic anemia
  • Elevated ESR
  • Thrombocytosis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Most accurate test for vasculitis

A

biopsy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

vasculitis tx

A

prednisone
refractory ritux or cyclophosphamide
next azathioprine/6-mercaptopurine and methotrexate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

5 specific features of poly arthritis nodosa

A
  • Abdominal pain 65%
  • Renal involvement 65%
    -Testicular involvement 35%
  • pericarditis 35%
  • HTN. 50%
    (NO lung involvement )
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What antigen is found in 30% of PAN patients

A

Hep B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Best first test and most accurate test for PAN

A

angiogram first

biopsy most accurate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

poly arthritis nodosa tx

A

prednisone and cyclophosphamide or ritux

acute life threatening dz may respond to plasma exchange

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

specific features of Granulomatosis w polyangitis

A

upper AND lower respiratory findings

c-ANCA (anti-proteinase 3)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Granulomatosis w polyangitis tx

A

prednisone and cyclophosphamide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Vasculitis + Eosinophillia + Asthma =

A

Churg Strauss (Eiosinophilc Granulomatosis w polyangitis)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Churg Strauss (Eiosinophilc Granulomatosis w polyangitis) sero marker sometimes

A

p-ANCA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Churg Strauss (Eiosinophilc Granulomatosis w polyangitis) tx

A

steroids + immunosuppressive (cyclophosphamide, azathioprine, or methotrexate) to help reduce steroid dose

IL-5 inhib like mepolizumab can induce remission in like 50% of cases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what meds can cause Churg Strauss (Eiosinophilc Granulomatosis w polyangitis)?

A

Leukitriene modifiers (zafirlukast, montelukast, or zileuton)

17
Q

patient presents w HA, Jaw claudication, vison changes, and tenderness of scalp. ESR is elevated. step to dx and tx

A

biopsy

steroids for Giant cell temporal arteritis

18
Q

Temporal arteritis med besides steroids

A

Tocilizumab (IL-6 inhibitors)

19
Q

Young asian women + diminished pulses =

A

Takayasu Arteritis

20
Q

most acurate test for Takayasu

A

Aortic Angiography or MRA

NOT biopsy!

21
Q

Cryoglobulinemia tx

A

For Hep c sofosbuvir/ledipasvir or any of the other combos

for cryoglobulinemia - ritux

vasculitis- cyclophosphamide is alternative to ritux

22
Q

What ancestory has Behcet

A

Middle Eastern/ Asia

23
Q

Behcet sx

A
  • oral and genital ulcers
  • ocular involvement ( uveitis/optic neuritis)
  • skin lesions (pathergy-hyperreactivity to needle stick = sterile abscesses
  • CNS disease 10% can have serious brain injury or spinal cord involvement
  • pulmonary artery aneurysm
24
Q

Behcet tx

A

prednisone and colchicine

sever dz may need cyclophosphamide

25
Q

Familial Mediterranean fever gene

A

MEVF

26
Q

Familial Mediterranean fever features (4)

A
  • recurrent abdominal pain, tenderness, and fever
  • episodic joint pain and chest pain
  • negative US/CT, neg stool, normal colonoscopy
  • elevated ESR, CRP, WBC, Fibrinogin
27
Q

Familial Mediterranean fever tx

A

Colchicine

28
Q

Familial Mediterranean fever long term complication

A

Amyloidosis

29
Q

Why can gout patients have normal uric acid levels especially during flare

A

it’s in the joints

30
Q

BP med that can cause gout attack

A

Thiazides

31
Q

Tx for gout attack

A

NSAIDS
Steroids if can’t use NSAIDS
Colchicine if no NSAIDS and first 24 hrs and no steroids

32
Q

Gout prevention

A
  • Weight loss/avoid triggers
  • Allopurinol (SE : rash allergic interstitial nephritis, hemolysis)
  • 2nd line Febuxostat- xanthine oxidase inhibitor
  • 3rd line uricase (pegloticase
  • rarely probenecid to increase urinary excretion- contra indicated with renal insufficiency

Step 3 (10 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions