Master the Boards: Cardiology 1 Flashcards
Most common cause of death US
CAD
8 CAD risk factors
- DM- most dangerous
- HTN
- Tobacco
- HLD
- PAD
- Obesity
- Inactivity
- Family Hx (female <65, male <55)
Most common cause of chest pain
GERD
3 Q’s to rule out CAD (only need 1)
- pleuritic-lung stuff
- positional- pericarditis
- tenderness- costochondritis
Physiology behind S3
rapid ventricular refilling during diastole extra fluid
Physiology behind s4
sound of arrival systole pushing blood into non compliant ventricle
Most accurate test for ischemic type pain
Trop or CK-MB, but do EKG first
What does troponin c bind to
Calcium to activate actin myosin interaction
What does troponin T bind to
Tropomyosin
What does troponin I bind to
blocks or inhibits actin myosin interaction
When to do dipyriamole or adenosine or dobutamine echo
-when patient cannot exercise to 85% of Max HR, COPD, amputation, reconditioning, weakness from previous stroke, lower extremity ulcer, dementia, obesity
When to do exercise thallium test or stress echo
-when EKG is unreadable for ischemia: LBBB, digoxin use, pacemaker, LV hypertrophy, any baseline abnormality of ST segment
ACS tx
Aspirin clopidogrel prasugrel (if angioplasty is done) nitrates and morphine (don't lower mortality) 02 BB- lower mortality but timing is not critical Acei Statin
Thrombolytics MOA
they activate plasminogen to plasmin which chops up fibrin into d dimers, this is why clots elevate levels of D-Dimer
Most common cause of death in CHF and MI
Ventricular arrhythmia brought on by ischemia