Mass Transport in Humans Flashcards
Blood flow through the heart, Heart structure, Pressure chambers, Valves, Cardiac output, Coronary heart disease, Antheroscleriosis, Thrombosis, Aneurysm, Risk factors, Gaseous exchange surfaces, Lung structure, Mechanism of breathing, Diffusion of gases, Pulminary ventilation, Lung disease, Mass flow, Circulation system, Major vessels, Structure of blood vessels, Tissue fluid, Lymphatic system
What is the function of the heart?
To pump blood around the body
How does blood flow through the heart (cardiac cycle)?
- Deoxygenated blood enters the heart through the vena cava and enters the right atrium. This increases the pressure in the right atrium above the pressure in the right ventricle causing the AV valve to open. The atrium muscles contract further increasing the pressure and forcing the remaining blood into the ventricle from the atrium
- The increased volume of blood in the ventricle increases the pressure above the atrium forcing the AV valve closed and opening the SL valve. The ventricular muscles contract further increasing the pressure and forcing the remaining blood into the lungs from the ventricle through the pulmonary artery
- Oxygenated blood enters the heart through the pulmonary vein and enters the left atrium. This increases the pressure in the left atrium above the pressure in the left ventricle causing the AV valve to open. The atrium muscles contract further increasing the pressure and forcing the remaining blood into the ventricle from the atrium
- The increased volume of blood in the ventricle increases the pressure above the atrium forcing the AV valve closed and opening the SL valve. The ventricular muscles contract further increasing the pressure and forcing the remaining blood through the aorta
Systole
Contractions of the heart muscle
Diastole
Heart muscle released
Branched off from the aorta and supply the heart muscle with blood
Coronary arteries
Why do valves only open one way?
It is due to tendons that anchor the valve
The volume of blood expelled from the left ventricle per minute
Cardiac output
Cardiac output formula
CO = SV X HR
SV - Stroke volume = the volume of blood expelled from the LV on one heart beat
HR - Heart rate = the number of cardiac cycles per minute
What is the process of atherosclerosis formation?
- The lumen of the artery is narrowed due to the build up of fatty deposits and chloestrol (atheroma) underneath the endothelium of the artery.
- Muscle fibres and calcium salts accumulate forming hard uneven patches called plaque. The plaque grows and bulges into the lumen of an artery
- The artheroma may cause reduced blood flow to the heart muscle cells beyond that point. This leads to muscle cells being deprived of sufficient oxygen during exercise. The cells respire anaerobically and produce lactic acid, which causes pain. The most common form of this problem is angina
- If the blood vessel is blocked completely the muscle cell gets no oxygen and die. This will cause a heart attack
What is the process of thrombosis formation?
- The plaque may rupture and trigger blood clotting over the damaged area. These clots build up very rapidly causing further blockage of the artery. This is known as a thrombus
- The clot may break up; travel in the blood stream and cause blockage elsewhere. This could lead to problems such as a stroke
What is the process of aneurysm formation?
. When the artery becomes blocked, blood flow through the area is restricted. The blood pressure builds up in front of the blockage and presses on the artery wall. This pressure causes the wall to weaken and it starts to bulge outwards. This is known as an aneurysm. The vessel may rupture, resulting in internal bleeding.
What 5 respiratory properties should surfaces have?
- Large SA
- Permeable
- Thin (low diffusion pathway)
- Moist (gases diffuse more readily in solution)
- Efficient transport system (maintains a concentration gradient)
Describe the lung structure
. Trachea - a tube like structure that carries air from he mouth to the lungs
. Bronchi - the trachea splits into two bronchi as it enters the lungs, which allows air to travel to the left and right lung
. Bronchioles - The bronchi further divides into smaller branches called bronchioles. These then supply the alveoli with air
Name the main structures of the alveoli and their function
. Provide a large SA for efficient diffusion
. Has a rich blood supply which maintains a large concentration gradient
. The cells are squamus which decreases the diffusion pathway
Fick’s law: Rate of diffusion =
(SA x Concentration gradient)/Diffusion distance
Inhalation
External intercostal muscles contact, internal intercostal muscles relax expanding the rib cage
The diaphragm contract and moves down
Lung volume increases
Pressure in lungs is less than outside so air moves in
Exhalation
Internal intercostal muscles contract, external intercostal muscles relax moving the rib cage in and down
The diaphragm contracts and moves up
The lung volume decreases
Pressure in lungs is more than outside so air moves out
How does oxygen diffuse into the blood?
As unoxygenated blood is pumped into the lungs and into the capillaries surrounding the alveoli a concentration is established, oxygen moves into the blood across the epithelial membrane and the wall of the capillary from a high concentration to a lower concentration. At the same time carbon dioxide moves from the blood into the alveoli