mass transport Flashcards
what is a haemoglobin
A group of chemically similar molecules found in a wide variety of organisms. Haemoglobins are protein molecules with quarternary structure that makes it efficient at loading and unloading oxygen.
Haemoglobin structure
Primary- sequence of amino acids in the four polypeptide chains
Secondary- each of the polypeptide chains coil into a helix
Tertiary- polypeptide folded into a precise shape
Quarternary- 4 polypeptide chains are linked together to form globular structure. Each polypeptide is associated with a haem group- which contain a Fe²+ ion. This makes a total of 4 o² molecules that can be carried around by a single haemoglobin molecule in humans
What is loading oxygen
Loading oxygen is where haemoglobin binds to oxygen. This takes place in the human lungs
What is unloading oxygen
Unloading oxygen is where the haemoglobin releases its oxygen which takes place in human tissues
Pros and cons of high affinity with oxygen
Positives are that it carrys a lot of oxygen. Negative is that is it hard to offload
Pros and cons with low affinities of oxygen
Positive is that it offload easily but negative is that it doesnt have much oxygen
What is the role of haemoglobin
The roles of haemoglobin is to transport oxygen. To be efficient at this it needs to be readily associated with oxygen at the surface and it need to be able to readily dissociate for oxygen to respiring tissues
What happens in the lungs
In the lungs, oxygen diffuses from the alveoli into the capillaries and into the red blood cells where is associates and forms oxyhaemoglobin
What is partial pressure
Partical pressure is measured of concentration of that gas in a mixture of gases
How is O² and PO² linked
When there is a higher concentration of O² there is a higher affinity of PO² in haemoglobin. When there is a low affinity, pO² promotes oxygen unloading.
Dissociation curve and CO²
When there is a low amount of CO² the curve shifts to the left. When there is a lot of CO² it shifts the the right
What is a single circulatory system
2 chambers which blood passes throughoncd a circuit
What is a double circulatory system
Hsart has 4 chambers and blood passes through the heart twice every circuit
What are the blood vessel tissue layers
Smooth muscle layer- contracts to control the flow of blood in arteries
Elastic layer- allows the vessel to stetch and recoil in arteries
Endothelium- thin layer lining which is smooth to reduce friction
Comparing arteries and veins
Arteries=AWAY
Veins= towards heart
Veins=VALVES
What happens when skeletal muscles contract
Compress the veins to maintain high pressure and push blood along
Pressure gradient
Blood always goes from high to low.
What is tissue fluid
Tissue fluid is formed by blood plasma leaking into capillaries. Surrounds the cells in the tissue and provides then with oxygen and nutrients. Net outflow of plasma from arterial end of capillaries due to high hydrostatic pressure.
What happens to excess tissue fluids
Its drained into vessels of lymphatic system
Heart structure
Right pumps deoxygenated, left pumps oxygenated.
What is cardiac muscles
Made up of cardiomyocytes, specialised cells with are myogenetic. Contract without nervous impulses.
Pulmonary artery
Connected to the right ventricle which Carrie’s deoxygenated blood to the lungs