mass transport Flashcards
describe the structure of haemoglobin
- globular
- water soluble
- 4 polypeptide chains
- each chain carries a haem group
describe the role of haemoglobin
- in red blood cells
- oxygen molecules bind to haem groups + are carried around the body to respiring tissues
name three factors affecting oxygen - haemoglobin binding
- partial pressure / concentration of oxygen
- partial pressure / concentration of carbon dioxide
saturation of haemoglobin with oxygen
how does partial pressure of oxygen affect oxygen-haemoglobin binding?
- as partial pressure of oxygen increases - affinity of haemoglobin for oxygen increases
- so oxygen binds TIGHTLY to haemoglobin
when partial pressure is LOW - oxygen is RELEASED from haemoglobin
how does partial pressure of carbon dioxide affect oxygen - haemolobin binding?
- as partial pressure of carbon dioxide increases - conditions = ACIDIC so haemoglobin CHANGES SHAPE
- affinity for haemoglobin decreases
- oxygen released from haemoglobin
- BOHR EFFECT
how does saturation of haemoglobin with oxygen affect oxygen - haemoglobin binding?
- hard for first molecule to bind
- once it does - changes shape so easier for 2nd and 3rd
this = POSITIVE COOPERATIVITY - harder for 4th oxygen molecule to bind as low chance of finding empty binding site
why does oxygen bind to haemoglobin in the lungs?
- high partial pressure of oxygen
- low concentration of carbon dioxide - high affinity
positive cooperativity
why is oxygen released from haemoglobin in respiring tissues?
- low partial pressure of oxygen
high concentration of CO2 in respiring tissues - decreased affinity
how does carbon dioxide affect the position of an oxyhaemoglobin dissociation curve?
- curve shifts to the right because haemoglobin’s affinity for oxygen decreases
relate structure of the atria to their function
- atria are thin walled and elastic so can stretch when filled with blood
relate the structure of the ventricles to their function
- thick + muscular walls
- pump blood under high pressure
- LEFT ventricle is THICKER as it has to pump blood all around the body
relate the structure of the arteries to their function
- the arteries have thick walls to handle HIGH PRESSURE without tearing
- muscular and elastic to control blood flow
relate the structure of the veins to their function
- thin walls due to lower pressure
- VALVES to ensure blood doesn’t flow backwards
- less muscular and elastic tissue as they don’t have to control blood flow
describe what happens during cardiac diastole
- heart = RELAXED
- blood enters atria - increases pressure - pushes open atrioventricular valves
- blood can flow to ventricles
- pressure in heart is LOWER than in arteries - semilunar valves remain CLOSED
what happens during atrial systole?
- atria CONTRACT
- pushing and remaining blood into the ventricles
what happens during ventricular systole?
- ventricles CONTRACT
- pressure increases - closing atrioventricular valves to prevent backflow
- opening semi-lunar valves
blood flows into the arteries
what does myogenic mean?
the heart’s contraction is initiated from within the muscle itself, rather than by nerve impulses
how is the structure of the capillaries suited to their function?
- walls one cell thick - short diffusion distance
- narrow - can permeate tissues and red blood cells can lie flat against the wall, effectively delivering oxygen to tissues
- numerous + HIGHLY BRANCHED = large surface area
what is tissue fluid?
- watery substance containing glucose, amino acids, oxygen and other nutrients
- it supplies these to the cells and removes any waste materials
how is tissue fluid formed?
- as blood is pumped through increasingly small vessels
- hydrostatic pressure created
- forces fluid out of the capillaries
- bathes the cells then returns to the capillaries when hydrostatic pressure is low enough
how is water transported in plants?
- xylem vessels
- long, continuous columns
- also provide structural support to the stem
explain the cohesion - tension theory
COHESION - hydrogen bonds between water molecules mean that they stick together
surface TENSION of the water also creates sticking effect
- so as water is lost through transpiration, more can be drawn up the stem