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ID Boards > Masquerades/Mimics > Flashcards

Masquerades/Mimics Flashcards

1
Q

MC rheum cause of FUO

A

giant cell arteritis (large vessel arteritis)

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2
Q

most specific test for SLE

A

anti-smith Ab

(anti dsDNA also quite specific)

(ANA very sensitive, but not specific)

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3
Q

anti-Ro/SSA

anti-La/SSB

A

Sjogren

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4
Q

c-ANCA

A

GPA

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5
Q

p-ANCA (antimeyloperoxidase)

A

eosinophilic granulomatosis w/ polyangiitis

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6
Q

fever

arthralgia/myalgia

extremity claudication

weak pulses

discrepant BP

A

takayasu (large vessel)

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7
Q

F, peripheral neuropathy, A/M, abd pn

cutaneous disease: nodules, ulcers, palpable purpura

multiorgan ischemia: look for GI, renal, and CNS (stroke-like) presentation

mimics IE w/ septic embolization

multiple aneurysms

A

polyarteritis nodosa (medium-vessel)

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8
Q

palpable purpura in LEs (any pressure or gravity-dep area)

arthritis/arthralgia

recurrent abd pain (can be severe)

glomerulonephritis

testicular pain (mimics epididymitis)

A

consider IgA vasculitis (formerly Henoch-Schonlein purpura)

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9
Q

recurrent F (lasts 1-3 days)

+

serositis (signs of peritonitis and pleuritis)

+

erysipelas-like erythema on legs

A

think of FMF

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10
Q

recurrent F (lasts >7 days)

migratory rash

eye involvement common (periorbital edema, conjunctivitis)

A

think TRAPS

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11
Q

elevated IgD (often IgA as well)

recurrent F (lasts 3-7 days)

usually presents 1st yr of life

triggered by vaccines

A

HyperIgG Syndrome (HIDS)

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12
Q

brief episodes of fever, conjunctivitis, and urticarial rash after cold exposure

A

cryopyrin-associated periodic syndrome (CAPS)

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13
Q

fever w/ aphthous ulcers, pharyngitis, and adenitis

3-6 days every 3-4wks like clockwork

A

PFAPA

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14
Q

50yo

daily fevers

chronic urticarial rash, skeletal hyperostosis, LAD

A

Schnitzler’s syndrome

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15
Q

F + cervical LAD in young (usually Asian) female

A

think Kikuchi’s disease

DX: bx w/ necrosis and significant histiocytic inflammation

TX: steroids

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16
Q

Non-infectious causes of pathergy

A

sweet’s syndrome

pyoderma gangrenosum

Behcet syndrome

(ALL demonstrate neutrophilic dermatosis on skin bx)

17
Q

Indolent, fever rare

Papule at site of trivial trauma –> painful ulcer w/ violaceous/red border and necrotic base

dx? and what assoc syndromes?

A

pyoderma ganrenosum

  • IBD MC
  • also inflammatory arthritis
  • solid organ/heme malignancy
18
Q
  • recurrent cellulitis (cartilage inflammation - not true cellulitis)
  • saddle-nose
  • cauliflower ear
  • sparing of ear lobe
  • parasternal joint involvement
A

buzz words for relapsing polychondritis

19
Q
  • evanescent, salmon-colored rash
  • multi-system illness
  • elevated ferritin
  • pharyngitis
  • Koebner (rash elicited by stroking skin/areas of pressure)
A

Adult Still’s buzz words

20
Q
  • acute onset
  • always febrile
  • neutrophilic dermatosis
  • Esp in setting of malignancy (AML), IBD, recent URI, vaccination, pregnancy
A

Sweet syndrome buzz words

21
Q
  • self-limited fever + cervical LAD (esp unilateral/posterior)
  • morbiliform exantham
  • variably leukopenic with atypical lymphocytes

LN bx: necrotizing histiocytic infiltrate (not neutrophils)

A

consider kikuchi disease

young women w/o racial/ethnic proclivity

22
Q
  • morning stiffness in proximal muscles (shoulder and hip)
  • difficulty initiating movement after prolonged immobility
A

buzzwords for PMR

23
Q

Infections a/w HLH

A
  • EBV (other herpesviridae)
  • HIV
  • histo
  • Ehrlichia
24
Q

triad: hilar LAD, acute arthritis (ankles MC), erythema nodosum

A

Lofgren sydnrome (Sarcoid)

***uveitis, aseptic meningitis w/ basilar enhancement, non-caseating granulomas

25
Q

Presentations of Behcets

A

mucosal ulcers on mouth/genitals

+

GI (vs CMV)

Aseptic meningitis (vs HSV)

Visual changes

Pathergy (needle/IV site)

26
Q

Minor Criteria for Still’s

A
  1. sore throat
  2. LAD
  3. HM/SM
  4. abnormal LFTs
  5. negative ANA/RF
27
Q

pustule at site of venipuncture

A

Behcets

28
Q

HLH clues

A
  • EBV (or other infection with progressive sx)
  • massively elevated ferritin
  • cytopenia with negative ID w/u
29
Q

periodic episodes of fevers + serositis PLUS

colchicine responsiveness

mediterranean ethnicity

A

FMF buzz words

30
Q

Causes of EN

A

“NODOSUM”

  • NO cause >50%
  • Drugs: sulfonamides, PCNs
  • Oral contraceptives
  • Sarcoid (Lofgren’s syndrome)
  • Ulcerative colitis (or Crohn’s or Behcets)
  • Microbes (EBV, HBV/HCV, strep, bartonella, TB, endemic fungi)
31
Q

Major criteria for Still’s

A
  1. Fever >39C for 1+ week
  2. Arthritis/arthralgia >2wk
  3. typical rash (during fevers) - salmon-evanescent
  4. WBC >10k (>80% PMNs)
32
Q

syndromes a/w saddle-nose deformity

A
  • Relapsing polychondritis
  • Lepromatous leprosy
  • Congenital syphilis
  • Leishmaniasis
  • GPA
  • Cocaine use
33
Q

young woman (asian ancestry)

carotidynia (pn w/ palpation)

decreased pulses

extremity claudication

visual changes

TIA

A

Takayasu arteritis

dx via arteriography

34
Q

longstanding asthma

new infiltrates and eosinophilia as steroids tapered

rash (tender nodules on extensor surfaces, purpura, ecchymosis, necrosis)

fever uncommon

A

buzz words for Churg-Strauss

ID Boards (24 decks)

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