march 16

Question 1

critical nitrogen containing molecules derived from amino acids

Answer 1

porphyrins,some hormones, neurotransmitters and purines/pyrimidines

Question 2

pophyrins

Answer 2

prostetic groups that bind Fe2+ or Fe3+

Question 3

Heme

Answer 3

binds one Fe2+, prosthetic group for hemoglobin, cytochromes and some enzymes

Question 4

Porphyrias

Answer 4

rare genetic diseases which lead to defects in biosynthesis of porphyrins and accumulation of intermediates

Question 5

acute intermittant porphyria

Answer 5

heterozygosity, abdominal pain, neuropsychiatric problems, motor weakness, requries environmenta/nutritional insult

Question 6

porphyria cutanea tarda

Answer 6

red urine, teeth fluoresce strongly in ultraviolet light, skin abnormally sensitive to light, anemic due to insufficient heme

Question 7

catecholamines

Answer 7

dopamine, norepinephrine, epinephrine

Question 8

creatine

Answer 8

phosphorylated form, creatine phosphate or phosphocreatine, is high energy compound found in muscle

Question 9

most glutamate ingested is oxidized in

Answer 9

small intestine

1. transport into epithelial cells
2. glutamate acted upon by several transaminases and glutamate dehydrogenase, product is å-keto glutarate

Question 10

steps in nitrogen assimilation(to biomolecules in plants and microorganisms

Answer 10

1. production of ammonia
2. incorporation of ammonia into glutamate and glutamine
3. incorporatoin of ammonia into glutamate and glutamine