Good questions Flashcards

1
Q

ß-oxidation

A

degradation of fatty
acids (acyl CoA), 2 carbons at a
time, producing acetyl CoA

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2
Q

Ketone bodies

A

energy souce(alternative to glucose)
formed by ketogenesis
utilized by extrahepatic tissues

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3
Q

Ketoacidosis

A

Ketone body metabolism in untreated diabetics

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4
Q

Cholesterol is primarily synthesized in

A

liver

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5
Q

activated isoprene is a precursor for

A

cholesterol

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6
Q

Lipoproteins

A

Are complexes of proteins and lipids

transport triacylglycerols and cholesterol in blood

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7
Q

statins

A

competitive inhibitors of HMG CoA redutase

- so cholesterol synthesis is inhibited

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8
Q

Familial Hypercholesterolemia

A

very high circulating cholesterol levels
sever artheroschlerosis
defective LDL receptor

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9
Q

NADPH is source of

A

biosynthetic reducing power for fatty acids, steroids, etc

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10
Q

first phase of PPP

A

oxidative generation of NADPH

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11
Q

second phase of PPP

A

nonoxidative interconversion of a variety of sugars

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