management of coronary artery alterations Flashcards
what is a widow maker
a block in the coronary artery
where is the left anterior descending coronary arteries
anterior and lateral wall of the left ventricle
where is the circumflex coronary artery
posterior and lateral wall of the left ventricle
where is the right coronary artery
SA node and AV node
where there is a block in the right coronary artery what happens
it blocks out the SA node and the AV node
what is atherosclerosis
begins as soft deposits of fat that harden with age over time hardening the arteries
what plays a major role in development if atherosclerosis
endothelial injury and inflammation
why would someone with atherlerscorosis be on antiplatelets
because if that build up of fat explodes all the platelets will go to close it and they pile on eachother blocking blood flow
what are some non-modifiable risks associated with coronary artery disease
over 65 years old, male, women if obese, African Americans, family history (1st degree), genetic predisposition
what are some major modifiable risks for coronary artery disease
HDL, LDL, Cholesterol (>200), triglycerides (>150), hypertension, smoking, low physical activity, obese (BMI>30), drug use, pernicious anemia
what levels do you want for HDL
high >60
what does HDL do
carry lipids away from arteries
what levels do you want for LDL
low levels <160
what does LDL do
carries lipids to arteries
what is an LDL goal for someone who is high risk
<70
what is a DM A1c goal for coronary artery disease
<7%
what are some ss of metabolic syndrome: insulin resistance disorders
central obesity, hypertension, abnormal serum lipids, elevated fasting BG
what are some contributing factors for coronary artery disease
DM, metabolic syndrome, psychological status, homocysteine level (pernicious anemia), substance abuse
what drug can lower lipids
atrovastain - inhibit cholesterol synthesis decreasing LDL and increasing HDL
what should you monitor for atrovastain
liver damage and myopathy
what nutrition therapy for coronary artery disease
decrease saturated fats, cholesterol, red meat, egg yols, whole milk increase complex carbs, fiber, omega 3 fatty acids
what is an antiplatelet therapy used for people over 50
asprin
how long are most CAD asymptomatic
years
what causes symptom angina
ischemia
what is ischemia
demand for myocardial oxygen exceeds what the coronary arteries can supple
what is stable angina
when resting it stops
what is unstable angina
not relieved at rest
what could be some reasons for unstable angina
acute coronary syndrome (myocardial infarction) which would be a Nstemi (non ST elevation myocardial infarction or a STEMI (ST elevation myocardial infarction)
what are some interventions for angina stable and unstable
percutaneous coronary intervention or coronary artery bypass graft
what is collateral cirulation
blockage in the arteries creates tiny branches around the artery to bypass the blockage - increase with chronic ischemia
what are some ss of stable chronic angina
predictable, relieved with rest, rarely requires aggressive treatment
what are some ss of unstable angina
new onset, not relieved with rest, pre-infarction
how is angina usually described
pressure, heaviness, or discomfort in chest
what is a medication that may be used with stable angina
nitroglycerin - 1st line
how does nitroglycerin work
dilates peripheral and coronary blood vessels
how do you take nitroglycerin
sublingually or nasal spray
if after taking nitroglycerin and there is no relief what should you do
call EMS
if some relief after taking nitroglycerin what should you do
take every 5 minutes for max of 3 does
can you take nitroglycerin if before angina happens
yes
what are some long acting nitrates
lsordill, limdur, nitroglycerin ointment, transdermal controlled release nitroglycerin
is ranolazine a 1st line drug
NO