Management - Cervical Cancer

Question 1

Factors to be considered

Answer 1

Fertility wishes
Ovarian preservation
Sexual function
Intercurrent medical disorders

Question 2

What does MDT decision making include?

Answer 2

Risks vs benefits

Question 3

What are the possible treatment options?

Answer 3

Surgery
Radiotherapy
Chemotherapy
Chemoradiotherpay

Question 4

Who is radical treatment considered for?

Answer 4

All patients expect those with widespread metastatic disease or gross bladder or rectal involvement

Question 5

What did the Cochrane review (2015) find in relation to surgery and and chemo/RT?

Answer 5

No evidence to support the addition of hysterectomy to RT or Chemo/RT to improve outcomes

Question 6

What did the Cochrane review (2012)/ Rogers et al (2012) find in relation to favouring RT or chemo/RT after radical surgery where there is a recurrence in IB, IB2 and IIA disease?

Answer 6

They found lower rates of disease progression but no improvement in overall survival in those who received adjuvant RT

Question 7

GFR test (chemo)?

Answer 7

Glomerular filtration rate

Question 8

What are some cisplatin toxicities?

Answer 8

Cardiac disorders, gastrointestinal, general disorders, haematological, hepatobiliary, nephrotoxicity, nervous system, oxotoxicity

Question 9

Managing chemo side effects - Increased risk of infection

Answer 9

Rise in temp - Sepsis risk