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Endocrine > Management > Flashcards

Management Flashcards

1
Q

Lowering Insulin resistance drug type

A

Thiazolidinediones

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2
Q

Amplifier of insulin

A

Incretins,

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3
Q

GLP

A

Glucose like polypeptide

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4
Q

GIP

A

Glucose dependent insulinotropic polypeptide

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5
Q

Lowering post-meal; reducing appetite; insulin like

A

Amylin analogue

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6
Q

Lowering complex sugar absorption and digestion

A

Alpha goucosidase inhibitors

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7
Q

Drug that activate AMPK

A

Metformin

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8
Q

Metformin other name

A

Biguanides

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9
Q

Metformin dosage

A

500 - 2550 mg / day; <1000mg direct

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10
Q

Contraindications for metformin

A

Renal; alcohol ; hepatic disease

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11
Q

Insulin secretagogue type of drugs

A

Sulphonylurea; meglitinde; d-ohenylalanine derivates

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12
Q

Sulphonylurea mechanism of action

A

Inhibits efflux potassium ions, efflux Ca, stimulates insulin release

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13
Q

1st gen sulphonylurea

A

Tolbu-; chlorpro-; lolaza-; MIDE

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14
Q

Contraindications of sulphonylurea

A

Cardiovascular diseases in elderly persons; hypoglycemia

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15
Q

2-binding sites sulphonylurea alike

A

Meglinitide, repaglinide

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16
Q

Rapid sulphonylurea

A

Nateglinide

17
Q

2nd gen of sulphonylureas

A

Glybur-; glipiz-; glimepr-; -IDE

18
Q

Thiazolidinediones mechanism of action

A

Ligands to peroxisome activated receptor gamma (PPAR gamma)

19
Q

PPAR gamma mechanism of action

A

Alter carbohydrate and lipid metabolism; modulated insulin transduction; increase adipocyte and tissues differentiation

20
Q

TZD drug name

A

Progliti-; rosiglita-; -ZONE

21
Q

TZD contraindications

A

Pregnancy; heart failure; fluid retention; weight gain

22
Q

Alpha glucosidase inhibitors mechanism of action

A

Competitive inhibitor of carbohydrate digestion-enzyme

23
Q

A-glucosidase inhibitors drug name

A

Aracbise and migitol

24
Q

A-glucosidase inhibitors contraindications

A

Inflamm bowel disease

25
Q

A-glucosidase inhibitors dosage

A

25-100 mg/premeal

26
Q

GLP drug name

A

Exena-; loragla-; -TIDE

27
Q

Contraindications of GLP-1

A

Pancreatitis

28
Q

DDP-4 agonists

A

Dipeptidyl peptidase-4

29
Q

DDP-4 name of drug

A

Sitag-; saxa-; linag-; -LIPTIN

Endocrine (4 decks)

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