Mammary Tissue Flashcards

1
Q

Outline the surface divisions of the breast

A
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2
Q

How is milk let down hormonally controlled?

A
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3
Q

Which ligamnets hold the breast tossue to the chest wall, they are particularly important when the breast is heavy and full of milk?

A

Cooper’s Ligaments

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4
Q

During pregancy which 3 hormones stimulate prolferation of breast glandular tissue?

A

Human Placental Lactogen and Progesterone from the placenta

Prolactin from the anterior pituitary

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5
Q

Which hormone inhibits prolactin in pregnancy to stop premature milk let down?

A

Progesterone

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6
Q

Outline to the breast tissue changed in pregnancy

A

Areola darkens

Mongomery glands make lipod fluid to lubricate the nipple

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7
Q

What is colostrum and what is ts function?

A

Intitially after birth a woman will make colostrum not milk. High immune cell and antibody secretion which is low in fat, coats the GI tract and has laxitive effects to sstiulate meconium

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8
Q

What is the fat content at the start of the feed relative to the end?

A

fat content increases throuput feeding session

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9
Q

Which immunoglobulin type is seen in the breast milk?

A

IgA

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10
Q

Which vitamin is commonly insufficent in breats milk?

A

D- may need supplement

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11
Q

What does breast milk contain?

A

Fat

Lactose

Viatmins

Micronutrients

Proteins

Immune stuff

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12
Q

Why do we lactate quickly after birth?

A

Delivery of the placenta means no placental progesterone inhibiting prolactin

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13
Q

What is milk let down.

A

Conditioned reflex

Baby suckles–> mechanoreceptor on alveoli detects–> intercostal nerve–> dorsal root ganglion—> spinal cord –> hypothalamus –> dopamine reduced, prolactine rises and oxytocin sent to post post pituatary

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14
Q

In the breast which cell type does prolactin act on?

A

Alveolar cells to stimulate milk production

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15
Q

Which hormone stimulates myepithelial cells in the breast when feeding?

A

Oxytocin

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16
Q

Which neurones make dopamine and are inhibited in lactation?

A

Prolactin Inhibiting Neurones

17
Q

When dopamine levels drop which cells secrete more prolactin?

A

lactotrophic cells

18
Q

Which hypothalamic cells make the oxytocin to send down the pituatary stalk?

A

Paraventricular cells

19
Q

Other than suckling what else could stimulate milk let down?

A

Sound of the babaies cry

20
Q

What is milk let down?

A

Combination of alveolar cells making milk and myopethlial cells contracting to push the mild down the ducts and out the nipple

21
Q

Why do new borns lose weight in the first week?

A

Small stomach (blueberry size)

Colostrum not full fat

22
Q

When do you expect the intial weight loss to be regained?

A

Week 2

23
Q

What causes glandular sturctures to involute when you stop breast feeding?

A

Fedding less

24
Q

Describe the content of breast tissue?

A

Adipose

Lobes- lobules

Milk ducts

Ligamnets

Fibrous connective tissue

Lymphatics

Nerves

Blood vessels

25
Q
A