malnutrition in disease and ageing Flashcards

principles nutrition screening, diagnosics, dinstinguish different nutrition disorders

1
Q

What is malnutrition?

A

A state resulting from lack of uptake or intake nutrition leading to altered body composition, leading to diminished physical and mental function and impaired clinical outcome from disease

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2
Q

Name three causes of malnutrition

A

Reduced food intake
impaired digestion
altered nutrient metabolism and excretion

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3
Q

How does reduced food intake occur in relation to symptoms to illness?

A

Anorexia can be due to symptoms of an ilness: nausea, vomiting, pain with eating, difficulty chewing or swallowing, depression or psychological

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4
Q

How does reduced food intake occur in relation to treatments?

A

side effects of medication, preperation to surgery of diagnostic tests, surgical resection of head, neck, mouth or esophagus.

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5
Q

What are the two wats to diagnose malnutrition

A

1: Having a BMI >18,5 kg/m2
2: Unintentional weightloss of 10% over indefinite amount of time. Or having 5>% weightloss over the last three months
In combination with BMI <20 kg/m2 if <70 years of age.

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6
Q

What is the prevalence of malnutrition in outpatiets

A

In oral macillofacial surgery 17% has severe undernutrition
Followed by oncology where 10% has severe undernutrition.

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7
Q

Where can we find the most malnourished people?

A

In the hospital and specifically in the geriartrics departments

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8
Q

What population in the community has the highest rate of undernutrition?

A

Home care: community-dwelling elderly with home care

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9
Q

What are the reasons for poor recognition by health care provider of malnutrition in community’s

A

There are limited screening by GP’s, there is no time, no training, no priority, nutrition is only a small part of medical curricula

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10
Q

What are the reasons adults have poor malnutrition awareness

A

people think malnutrition only occurs in poor countries and at times of water. Also losing weight is normal aspect of aging. Weightloss is often appreciated.

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11
Q

When do you speak of acute diseased related malnutrition?

A

When there is highly pronounced stress metabolism. Patients in ICU, Trauma, sepsis or after major surgical procedures are at high risk.
CRP >50 mg/l
increased corticosteroid or catecholamine release
resistance to insulin and growth hormones
no/reduced foot intake

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12
Q

Chronic disease related malnutrition is

A
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13
Q

When do we speak of chronic disease related malnutrition with inflammation?

A

Seen in late stage organ diseases that are complicated by catabolic inflammatory responses: cancer, cachexia, Chron’s disease, COPD, chronic kidney disease

It is featured by:
weightloss
reduced BMI
reduced muscle mass and function
Combined with underlying disease that displays biochemical indices of ongoing inflammatory activities (CRP>5 mg/l)

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14
Q

How can CACHEXIA be defined?

A

It is a multifactorial syndrome characterized by an ongoing loss of skeletal muscle mass that cannot be reversed by convential nutritional support. It leads to progessive functional impairment

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15
Q

What mechanisms can cause disease related malnutrition without inflammation?

A

It is featured by:
Weight loss
low BMI
reduced muscle mass and function
combined with underlying disease

Is seen in:
dysphagoa, malabsorption, neurologic disorders (Parkinsons, ALS, stroke)
dementia/ cognitive dysfunction
psychiatric conditions like anorexia nervosa and depression

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16
Q

What is the etiology of Sarcopenia

A

Age related: sex hormones, apoptosis, mitochondrial dysfunction
Cachexia
Neurodegerative diseases: motoneuron loss
Disuse: immobility, psychical inactivity, zero gravity
Endocrine: corticosteroids, GH, IGF, thyroid, insulin resistance

17
Q

What are the three parameters of SARCOPENIA?

A

2018:
1. low muscle strength
2. low muscle quantity/quality
3. low physical performance