Malnutrition and Nutritional Assesement (Complete) Flashcards

1
Q

Define malnutration

A

State in which lack of uptake or intake of nutrition leads to a altered body compisiton and cell body mass which results in impaired physical and mental function.

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2
Q

Malnutrtition tends to be highest in which age groups?

A

The young and elderly (more common in females)

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3
Q

Which 2 hospital specialty wards has the highest prevalence of mulnutrition in patients?

A

Oncology

Care of the elderly

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4
Q

Malnutrition is most common in patients with what group of diseases?

A

Gastrointestinal diseases

N.B. Also prevalent in patients with chronic diseases such as cancers, diabetes ect

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5
Q

70% of patients who have stayed in hospital end up losing weight (muscle mass vs fat). Suggest some hospital related factors that can lead to malnutrition in hospitals.

A
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6
Q

Malnutrition can lead to poorer physical and functional decline, leading to poorer clinical outcomes. List examples of the impact of malnutrition in terms of clinical outcomes.

A

Increases the risk of:

Mortality

Septic and post surgical complications

Length of hospital-stay

Pressure sores

Re-admissions, dependency

Reduces:

Wound healing

Response to treatment

Rehabilitation potential

Quality of life

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7
Q

What is the economic consequence of malnutrition?

A

Costs the economy £19.6 billion on public health expenditure due to patients requiring more care

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8
Q

What is the most common screening tool in the UK for malnutrition?

A

Malnutrition Universal Screening Tool (MUST)

N.B. It is not a assesment or diagnostic for malnutrition. It only helps to identify risk.

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9
Q

What 3 components are assessed in MUST to determine the risk of malnutrition?

A

BMI

Weight loss (unexplained weight loss)

Acute disease effect score (looks at whether acute disease is reducing or will reduce food intake)

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10
Q

What is the next step of action if a MUST score shows a patient is at high risk of malnutrition and may benefit from treatment (e.g. are not at imminent death)?

A

Refer to a dietician

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11
Q

What is the role of a dietician when dealing with malnourished patients?

A

Able to carry of an extensive nutritional assesment and diagnose malnutrition.

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12
Q

List the 3 components of a systematically approached nutritional assesement

A

Anthropology (to measure different compartments of the body and how they have been affected by malnutrition)

Biochemistry (Tests can be used to estimate nutritent availability in fluids and tissues)

Clinical history (provide insight into nutrient related problems) [E.g. clinical conditions, dietary constrictions, socioeconomic statuses]

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13
Q

What is the most reliable way to estimate energy expenditure and guide energy prescriptions in a nutritional assesment?

A

Indirect caliometry

N.B. However has many restrictions which limits its use in clincal setting. Therefore predictive equations are done instead.

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14
Q

According to NICE guidelines, providing nutrition support should be considered in people who are either? (2)

A

Malnourished

At risk of malnourishment

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15
Q

List 3 ways a patient can be considered malnourished according to NICE guidelines

A

BMI < 18.5 kg/m2 or

Unintentional weight loss >10 % past 3 - 6 / 12 months

BMI < 20 kg/m2 + unintentional weight loss > 5 % past 3 – 6 months

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16
Q

List 2 ways a patient can be considered at risk of being malnourished according to NICE guidelines

A

Have eaten little or nothing for > 5 days and / or are likely to eat little or nothing for the next 5 days or longer

or

Have a poor absorptive capacity, and / or have high nutrient losses and/or have increased nutritional needs from causes such as catabolism.

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17
Q

Define artificial nutritional support

A

The provision of enteral or parenteral nutrients to treat or prevent malnutrition.

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18
Q

According to the algorithm by Stratton and Elia for malnutrition support, when should a patient be considered for enteral tube feeding?

A

Oral nutrition is not possible and GI tract is functional and accesible

Or oral nutrition is possible but regularly monitored intake shows inadequate nutrition after receiving oral nutritional support

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19
Q

According to the algorithm by Stratton and Elia for malnutrition support, when should a patient be considered for parenteral tube feeding?

A

Oral nutrition not possible or safe

GI tract is not functional and inaccesible

20
Q

Give 2 examples of artificial nutritional support routes and state which of the two is superior?

A

Enteral nutrition (Superior as it involves the GI tract) [EN]

Parenteral nutrition [PN]

21
Q

What is the aim of parenteral nutrition? (PN)

A

Aim is to return to enteral nutrition as soon as possible and oral nutrtion of clinically possible

22
Q

What are the different types of enteral feeding methods depending on access points?

A

Put a tube down the nose and the tube can end up in different access points:

Nasogastric tube (Stomach) [NGT]

Nasoduodenal tube [NDT]

Naso-jejunal tube [NJT]

Or for long term (>3 months) of enteral nutrition is required, may require a gastrostomy or jejunostomy (Directly into stomach or jejunum)

23
Q

For a patient requiring long-term enteral nutrition (> 3 months), what type of enteral nutrition method would be most suitable?

A

A gastrostomy (if gastric feeding possible)

Jejunstomy (If gastric feeding not possible)

24
Q

For a patient in which gastric feeding is not possible, what is the most suitable enteral nutrition feeding methods? (2)

A

NDT (Naso-duodenal tube)

NJT (Naso-jejunal tube)

25
Q

Give an example of a condition which can prevent gastric feeding as a possibility for enteral nutrition and suggest what the next step of action should be in these patients.

A

Gastric outlet obstruction

NGT is contraindicted in these cases so should give patient a NJT

26
Q

List some complications associated with enteral feeding. (10)

A

Mechanical:

Misplacement

Blockage

Buried bumper (Bumber erodes abdominal wall and gets stuck between gastric wall and skin)

Metabolic:

Hypergylcaemia,

Deranged electrolytes

GI:

Aspiration (Food enters lung)

Nasopharyngeal pain

Laryngeal ulceration

Vomiting

Diarrhoea

27
Q

What is a serious complication associated with enteral feeding and how can this be avoided?

A

Misplaced NG tube

Must take an aspirate sample from the NG tube and measure the pH

Aspirate should be pH < 5.5 (indicates GI acidic content)

if aspirate pH > 5.5 then they need an X-ray interpreted by trained professional following NPSA guidelines

28
Q

A regular aspirate sample has been taken from a patients NGT. The sample has shown a pH of 6.8. What is the next course of action?

A

pH > 5.5 so will need a CXR

Imaging should be interpretted by a proffesional following National Patient Safety Agency (NPSA) safety guidelines

29
Q

Define parental nutrition

A

The delivery of nutrients, electrolytes and fluid directly into venous blood.

30
Q

What are 2 indications which suggest that a patient may benefit from perental feeding as the method of artifical nutritional support?

A

An inadequate or unsafe oral and/or enteral nutritional intake

OR

A non-functioning, inaccessible or perforated gastrointestinal tract

31
Q

What is the most common access point for parenteral nutrition?

A

•Central venous catheter (CVC): tip at superior vena cava and right atrium.

N.B. Different centra venous catheters for short/long-term use

32
Q

How is parenteral nutrition composition determined for individual patients?

A

Can administer ready made or ‘scratch’ bags

The dietician also liases with the MDT to determine the electrolyte/fluid targets for the day

33
Q

List some complications associated with parenteral feeding

A

Catheter related infections

Mechancal complications:

Pneumothorax

Haemothorax

Thrombosis

Cardiac arrythmias

Metabolic:

Deranged electrolyttes

Hyperglycaemia

Hypertriglycerideamia

34
Q

What is the most abundant circulating protein in the plasma of healthy individuals? What can it be useful in predicting?

A

Albumin

Low levels are useful in predicting poor progonosis

35
Q

Albumin is considered a negative acute phase protein. State what this means

A

Negative acute phase proteins are proteins that lower in levels in response to acute inflammatory response

36
Q

Explain the acute phase resposne which results in lower albumin levels

A

When there is an inflammatory stimulus (e.g. muscle breakdown), it triggers the activation of macrophages and monocytes which release cytokines such as IL-6 and TNF.

Cytokines then act on the liver and upregulate some proteins whilst downregulating others such as albumin

37
Q

Can low albumin levels be a viable indication for malnutrition?

A

No as albumin levels lower in response to inflammatory stress which can be due to multiple things such as tissue injury, infection, muscle breakdown, stress ect.

E.g. hypoalbuminaemia in obese trauma patients

37
Q

What is refeeding syndrome? (RFS)

A

A group of biochemical shifts & clinical symptoms that can occur in the malnourished or starved individual on the reintroduction of oral, enteral or parenteral nutrition.

38
Q

A group of biochemical shifts & clinical symptoms that can occur in the malnourished or starved individual on the reintroduction of oral, enteral or parenteral nutrition.

A

Refeeding syndrome

39
Q

What are some of the symptoms and consequences of refeeding syndrome? (7)

A

Arrhythmia, tachycardia, CHF → Cardiac arrest, sudden death

Respiratory depression

Encephalopathy (Damage to brain)

Coma

Seizures

Rhabdomyolysis (breakdown of muscle tissue leading to muscle fibres circulating in blood and can lead to kidney damage)

Wernicke’s encephalopy (brain complications due to lactic acid in brain due to thiamine deficiency needed for glucose to not be metabolised anerobically)

40
Q

Summarise the pathogenesis of refreeding syndrome

A

When malnourished, the body switches to a catabolic state (gluconeogeneis, glycogenolysis, increased glucagon, proteinolysis)

Protein, fat, mineral and elctrolyte depeltion results in salt and water intolerance (low concentration in plasma)

Refeeding then triggers a anabolic state resulting in insulin secretion

This promotes increased protein and glycogen synthesis, increased electrolyte uptake, glucose uptake and utilization of thiamine.

This consequently depletes plasma stores as they are already low, resulting in many complications such as hypokalaemia, thiamine deficiency, hypomagnesia, salt and water retention (e.g. oedema).

These depletions can result in the clinical manifestations of refeeding syndrome (e.g. arrythmia, werknickes encephalopathy due ti thiamine deficiency)

41
Q

According to the NICE guidlines, RFS (refeeding syndrome) risk can be categorised as at risk, high risk, extremely high risk.

What would place a patient at risk of RFS?

A

Very little food or no food intake for > 5 days

42
Q

According to the NICE guidlines, RFS (refeeding syndrome) risk can be categorised as at risk, high risk, extremely high risk.

What would place a patient at high risk of RFS?

A

> 1 or more of the following:

BMI < 16 kg/m2

Unintentional weight loss > 15 % 3 – 6 /12

Very little / no nutrition > 10 days

Low K+, Mg2+, PO4 prior to feeding

OR > 2 or more of the following:

•BMI < 18.5 kg/m2

Unintentional weight loss > 10 % 3 – 6 / 12

Very little / no nutrition > 5 days

PMHx alcohol abuse or drugs (insulin, chemotherapy, antacids, diuretics)

43
Q

According to the NICE guidlines, RFS (refeeding syndrome) risk can be categorised as at risk, high risk, extremely high risk.

What would place a patient at extremely high risk of RFS?

A

BMI < 14 kg/m2

Negligible intake > 15 days

44
Q

What is the management plan for a patient at risk of refeeding syndrome?

A

Micronutrients from onset of feeding (e.g. 10-20kcal/kg with 40-50% of the energy coming from carbohydrates [CHO])

Correct and monitor electrolytes daily

Administer thiamine from onset of feeding

Monitor fluid shifts and minimise risk of fluid and Na+ overload