Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Hematology > Malignancy > Flashcards

Malignancy Flashcards

1
Q

Allogenic bone marrow

A

Donor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Autologous bone marrow

A

OWN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Reed Sternberg Cells

A

Hodgkin’s Lymphoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Causes Hodgkin’s Lymphoma

A

malignant cells from B lymphoctyes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Painless, lympadenopathy, fever, night sweats, weight loss

A

Hodgkin’s Dx

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Arises in a single lymph node, spreads in an orderly fashion

A

Hodgkin’s Dx

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Dx for Hodgkin’s Lymphoma

A

lymph node excisional biopsy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Stage I Hodgkin lymphoma

A

1 lymph node region involved

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Stage II Hodgkin lymphoma

A

2 or more lymph node regions involved, on one side of the diaphragm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Stage III Hodgkin lymphoma

A

Lymph node regions involved on both sides of the diaphragm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Stage IV Hodgkin lymphoma

A

Disseminated disease w/ extranodal involvement

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

“A” Hodgkin

A

no constitutional symptoms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

“B” Hodgkin

A

fever, night sweats, weight loss

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

“X” Hodgkin

A

bulky disease; Mediastinal involvement

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Dx for Non-Hodgkin lymphoma

A

tissue biopsy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Malignant proliferation of plasma cells originating in the bone marrow

A

Multiple Myeloma (Plasma Cell Myeloma)

17
Q

Excess of what immungobulin in multiple myeloma?

A

IgG; Monoclonal gammopathy

18
Q

Rouleaux Formation

A

Multiple myeloma

19
Q

Bence jones protein

A

Multiple myeloma

20
Q

Hypercalcemia

A

Multiple myeloma

21
Q

Monoclonal protein (M-protein) on SPEP and/or UPEP

A

Multiple Myeloma

22
Q

Lytic lesions

A

Multiple Myeloma

23
Q

Asymptomatic pt w/ hypercalcemia, increase serum protein and anemia

A

Multiple myeloma

24
Q

Txt for multiple myeloma

A

biologic agents (Lenalidomide, Bortezomib) and Dexamethasone

25
Q

Most common childhood malignancy

A

Acute lymphoblastic leukemia

26
Q

Philadephia Chromosome

A

Acute lymphoblastic leukemia

27
Q

What are lymphoblasts in “ALL” described as?

A

TdT postiive

Negative for peroxidase and Sudan black histochemical stains

28
Q

Auer rods

A

Acute Myeloid Leukemia

29
Q

How do myeloblasts look in AML?

A

positive for peroxidase and sudan black histochemical stains

30
Q

Most common form of leukemia in adults in the US

A

Chronic lymphocytic leukemia (CLL)

31
Q

Proliferation of mature appearing lymphocytes in peripheral blood that invade bone marrow, spleen, and lymph nodes

A

chronic lymphoctyic leukemia

32
Q

Hallmark is Lymphocytosis

A

Chronic Lymphocytic Leukemia (CLL)

33
Q

Smudge cells present

A

Chronic lymphocytic leukemia

34
Q

Elevated WBC >150,000

35
Q

Hallmark bcr/abl gene is detected by PCR test in peripheral blood or bone marrow biospy

A

Chronic Myeloid Leukemia

36
Q

Txt of choice for CML?

A

Imatnib mesylate (tyrosine kinase inhibitor)

Hematology (4 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions