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ACE THIS EXAM GIRL! Flashcards

1
Q

Most common cause of anemia worldwide?

A

iron deficiency anemia

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2
Q

Most common cause for iron deficiency anemia?

A

bleeding

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3
Q

Spoon nails, cheilosis

A

iron deficiency anemia

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4
Q

Microcytosis, normal iron level and family hx

A

Thalassemia

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5
Q

What is the definitive dx for sideroblastic anemia?

A

bone marrow

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6
Q

Macrocytic anemia

A

Vitamin B12

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7
Q

What is the number 1 cause of Vit B12 deficiency?

A

inability to absorb

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8
Q

What test determines the underlying cause of anemia?

A

Shilling TEST

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9
Q

Most common cause of folate deficiency

A

inadequate dietary intake

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10
Q

Diagnostic RBC folic acid level?

A

<150 mg/ml

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11
Q

African African males and Mediterranean population

A

G6PD

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12
Q

Fava beans

A

G6PD

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13
Q

Heinz Bodies

A

G6PD

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14
Q

Primary cause of hospitilzations

A

acute vaso-occlusive crisis

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15
Q

Diagnosis of choice for sickle cell?

A

Hgb electrophoresis

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16
Q

Autoimmune suppression of hematopoiesis by a T cell mediated cellular mechanism

A

aplastic anemia

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17
Q

Basophillic stippling, target cells, poikilocytosis

A

Thalassemia

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18
Q

Lead line gum, foot drop, long bones lead lines

A

Sideroblastic Anemia

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19
Q

Elevated level of MMA and Homocysteine

A

B12

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20
Q

Risk factor for admin of Vit B12

A

Hypokalemia

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21
Q

Northern European and African American

A

Pernicious anemia

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22
Q

MC cause of folate acid deficiency?

A

inadequate dietary intake

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23
Q

RBC folic acid level?

A

<150 mg/ml

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24
Q

“Bite” or blister cells?

A

G6PD

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25
Txt for G6PD?
self limited
26
Coombs test negative
Hereditary Spherocytosis
27
Disorder of RBC membrane, causing spherical shape
Hereditary Spherocytosis
28
Howell- Jolly bodies, and target cells (Hyposplenism)
Sickle cell Anemia
29
DOC for sickle cell?
Hgb electrophoresis
30
Panctyopenia
aplastic anemia
31
pallor, purpura, petechiae
aplastic anemia
32
TXT for aplastic anemia
supportive care
33
MC form of thrombocytopenia
immune thrombocytopenia
34
Hemorrhagic bullae
immune thrombocytopenia
35
Txt for immune thrombocytopenia?
corticosteriods
36
TTP defeiciency?
von Willebrand's factor
37
Schistocytes, helmet cells
TTP
38
TXT for TTP?
Plasmapheresis
39
Hemolytic Uremic Syndrome bacteria?
E.coli
40
TXT for HUS?
supportive care
41
Decrease platelets and schistocytes?
DIC
42
What does HELLP stand for?
Hemolysis, Elevated Liver enzymes, Low Platelets
43
Severe form of DIC?
HELLP
44
Missing Factor 8
Hemophilia A
45
Missing Factor 9
Hemophilia B
46
Missing Factor 11
Hemophilia C
47
Hemarthrosis?
Hemophilia A
48
Ashkenzai Jewish descent?
Hemophilia C
49
MC inherited bleeding disorder
Von Willebrand's Disease
50
MC von Willebrand type?
Type I
51
TXT for von Willebrand?
DDAVP
52
Des gamma carboxy prothrombin marker?
Vitamin K
53
Two factors the liver doesn't produce?
VIII and vWF
54
Deficiency in antithrombin III?
Antithrombin III
55
Recurrent DVT and PE
Protein C and S deficiency
56
MC of Protein C and S?
C
57
Activated Protein C resistance test?
Factor V Leiden
58
4 acquired hyper coagulability?
pregnancy malignancy OCP Lupus anticoagulant
59
Mutation in JAK2?
Polycythemia Vera
60
Hemotocrit > 54% males, 51% females
Polycythemia Vera
61
TXT for polycythemia vera?
Phlebotomy
62
High altitudes?
Polycythemia vera
63
Reed Sternberg cells
Hodgkin's lymphoma
64
Abdominal pain or fullness?
Non-Hodgkin's lymphoma
65
M-protein
Multiple Myeloma
66
Lytic lesions, "Moth eaten"?
Multiple Myeloma
67
Bence jones
Multiple Myeloma
68
Rouleaux formation and hypercalcemia
Multiple Myeloma
69
TXT for multiple myeloma?
biologic agents (IMIDs) and Dexmethasone
70
Most common childhood malignancy?
Acute Lymphoblastic Leukemia
71
Philadelphia chromosome w/ poor prognosis?
ALL
72
negative peroxidase and sudan black stain
acute lymphoblastic leukemia
73
MC form of leukemia in adults in US
Chronic lymphoblastic leukemia
74
Proliferation of MATURE lymphocytes in peripheral
CLL
75
Smudge cells?
Chronic Lymphoblastic leukemia (CLL)
76
Lymphocytosis?
CLL
77
Auer rods?
Acute myeloid leukemia (AML)
78
Peroxidase and sudan black stain posItive
acute myeloid leukemia (AML)
79
Philadelphia chromosome
chronic myeloid leukemia (CML)
80
TXT for CML?
Tyrosine kinase inhibitor (Imatnib)
81
Dx for chronic myeloid leukemia?
PCR
82
MC type of Hodgkin?
Classic
83
Staging of Lymphomas?
Stage I- 1 lymph node region involved Stage II- 2 or more lymph node regions involved, one side of diaphragm Stage III- lymph nodes regions on both sides of diaphragm Stage IV- disseminated w/ extra nodal involvement
84
Difference between folic and B12 defiecincy
neuro abnormalities
85
How do you distinguish between hemolytic anemia's?
Coombs test | Hgb Electrophoresis
86
TXT for chronic anemia?
Darbepoetin, Erythropoietin
87
List four disease states in which you may find | basophilic stippling
Lead poisoning, beta or alpha thalassemia, sideroblastic anemia,
88
What molecule binds iron in the blood stream?
Transferrin
89
Inability to absorb vitamin B12 due to lack of | intrinsic factor is what disease?
Perinicous anemia
90
Will unconjugated bilirubin be high or low in a | patient with sickle cell disease?
high
91
Would anemia of chronic disease most likely be | macrocytic, normocytic or microcytic?
normocytic
92
Will the serum ferritin be high or low in a patient | with iron deficient anemia?
It will almost always be low
93
G6PD deficiency follows what pattern of | inheritance?
X-linked
94
Strict vegans are at risk for what type of anemia?
B12 deficiency anemia
95
The term Philadelphia chromosome should make | you think of what diagnosis?
Chronic myeloid leukemia
96
List the three diagnosis you should be thinking of if | a question includes Heinz bodies.
G6PD deficiency anemia, chronic liver | disease, alpha thalassemia
97
Normal range for MCV?
80-100
98
Are target cells seen in mild or severe iron | deficiency anemia?
Severe
99
How do you treat a sickle cell crisis?
Fluids, oxygen, pain medication, | transfusion may be necessary
100
A patient of Mediterranean descent is a clue for | which type of anemia?
Beta thalassemia

Hematology (4 decks)

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