malignancy Flashcards
where do primary brain tumours originate from
glial cells
name some risk factors for primary brain tumours
inherited syndromes: neurofibromatosis, CHL, tuberous sclerosis
ionising radiation
immunosuppression
name some global symptoms of a primary brain tumour
headache, N+V, reduced GCS, pupils
name some focal symptoms of a primary brain tumour
paresis, dysphasia, numbness, seizure, visual symptoms, discoordination
name some characteristics of a headache associated with a primary brain tumour
worse in the morning (wakes them up)
worse on coughing and leaning forward
associated with or be made worse by vomiting
diagnosis a primary brain tumour
MRI +/- CT scan
how do we grade brain tumours
1-4 based on lesion biopsy
what can be used to relieve headache caused by tumour
dexamethasone
palliative management of primary brain tumours
radiotherapy + chemotherapy
what are the 4 most common origin sites of metastatic brain cancer
lung
breast
skin (melanoma)
kidney