Malignancies - neuroblastoma Flashcards
1
Q
what is a neuroblastoma - where is it from
A
from neural crest cells - can end up in adrenal medulla or anywhere along sympathetic nervous chain
2
Q
age range for neuroblastoma?
A
mostly under 5 years old
3
Q
presentation for neuroblastoma?
A
pale, weight loss
abdominal mass hepatomegaly
bone pain, limp (mets)
paraplegia, cervical lymph nodes, proptosis, periorbital bruising, skin nodules
hypertension
4
Q
investigations for neuroblastoma?
A
high VMA/HVA
biopsy diagnostic
5
Q
what are VMA/HVA?
A
breakdown products of adrenaline
6
Q
treatment for neuroblastoma?
A
early - cut it out
late - chemo
