Male Endocrinology Flashcards
what are the three successful functions of the testes
- adequate secretion GnRH from hypothalamus
- secretion of LH and FSH from pituitary
- secretion of steroids from the testes
basal release
GnRH (every 3-6 hours)
what hormones experience episodic release pattern based on response to GnRH
LH and FSH
why does FSH have lower amplitude than LH
negative feedback loop of inhibin
what does the anterior pituitary release
LH and FSH
what cells are produced by LH
leydig cells
what cells do FSH produce
sertoli cells
what do the leydig cells produce
testosterone
what does sertoli cells aid in the production of
- estradiol
- DHT
- androgen binding protein (ABP)
- inhibin
what does inhibin depress
FSH
which cells are on the outside of the seminiferous tubules
leydig cells
what cells are in the inside of the seminiferous tubules
sertoli cells
how many carbons does progesterone have
21
how many carbons does androgens have
19
direction LH and FSH would go if male was castrated
increase
direction testosterone would go if pituitary was removed
decrease
direction LH would go when GnRH is decreased
increase
hypothalamic center active in males
tonic
