Genetic and Gondal Sex. Differentiation Flashcards

1
Q

how is sex defined

A
  1. genetic
  2. gonadal
  3. internal genitalia
  4. external genitalia
  5. hypothalamic
  6. physiological/behavioral
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2
Q

in mammals, what is the male

A

XY
- heterogametic

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3
Q

in mammals, what is the female

A

XX
- homogametic

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4
Q

in birds, what is the male

A

ZZ
- homogametic

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5
Q

in birds, what is the female

A

ZY
- heterogametic

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6
Q

what chromosome is essential for life

A

X

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7
Q

what is used for blood clotting

A

anti-hemolytic factors

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8
Q

what does the AR gene code for

A

androgenw

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9
Q

DAX-1 gene

A

sex determination on X chromosome for both male and female

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10
Q

what is the gene that causes the formation of female barr body

A

XIST gene

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11
Q

what is the SRY gene

A

gene on Y chromosome responsible for male sexual development

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12
Q

what does the SRY protein do

A

activates genes that cause biopotential undifferentiated gonads to differentiate testes

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13
Q

bipotential

A

ability to go either direction/either sex

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14
Q

undifferentiated

A

hasn’t picked whether male or female

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15
Q

what do the biopotential undifferentiated tissue become

A

biopotential undifferentiated gonads
- form either ovaries or testes

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16
Q

what do primordial germ cells give rise to

A
  • sperm or egg (germ cells)
  • colonize gondal ridge
17
Q

how do PGCs differ from somatic cells

A
  • larger
  • can move in crawling motion
  • motile
  • secrete lytic enzymes
18
Q

what is located inside the yolk sac

A

primordial germ cell

19
Q

how do the PGCs know to migrate from yolk sac

A

telopheron
- chemical that signals where to go

20
Q

what is the result of mitosis of the PGC cells

A

primitive sex cords

21
Q

what do the PGCs become in females

22
Q

what do the biopotential undifferentiated gonads become

23
Q

which side foes the female repro tract develop on

24
Q

what does the left ovary in birds produce and release

25
what do PGCs become in males
spermatogonia
26
SRY--->SRY--->
differentiates primitive sex cords into seminiferous tubules
27
SRY protein---> SOX9--->
Sertoli cells
28
what are called the nurse cells
Sertoli cells
29
what is the job of Sertoli cells
- contain spermatogonia - responsible for spermatogenesis - produce and release AMH
30
SRY protein--->SOX9--->Sertoli cells--->
DHH
31
what do DHH produce
Leydig cells
32
what is the function of the Leydig cells
produce and release testosterone