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Therapeutics > Malaria & RMSF > Flashcards

Malaria & RMSF Flashcards

1
Q

The most worrisome parasite for malaria is plasmodium _____

A

falciparum

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2
Q

In which stage do people get sick from malaria, liver or blood?

A

Blood

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3
Q

The incubation period for malaria can range from __-30 days

A

7-30 days

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4
Q

P. ___ and P. ____ may be in dormant stages for months and have delayed symptoms by weeks to months

A

P. ovale and P. vivax

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5
Q

What needs to be tested for when being considered for taking primaquine?

A

glucose-6-phosphate dehydrogenase (G6PD) - levels should be positive if taking primaquine

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6
Q

Atovaquone/Proguanil should be taken 1-2 ___ before travel and for ___ days after traveling

A

1-2 days before travel and for 7 days after traveling

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7
Q

Atovaquone/Proguanil is a once daily medication (T/F)

A

True

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8
Q

Which malaria medication should be avoided in pregnancy and severe renal impairment?

A

Atovaquone/Proguanil

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9
Q

Are pediatric tablets available for atovaquone/proguanil?

A

Yes

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10
Q

Chloroquine should be taken 1-2 ____ before traveling and for ____ weeks after traveling

A

1-2 weeks before traveling and for 4 weeks after traveling

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11
Q

Chloroquine is a daily medication (T/F)

A

False, weekly medication

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12
Q

Patients taking ______ chronically may not need to take chloroquine

A

hydroxycholorquine

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13
Q

Chloroquine is good for short trips (T/F)

A

False, good for long trips due to weekly dose

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14
Q

Which malaria medication can exacerbate psoriasis?

A

Chloroquine

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15
Q

What needs to be checked before starting chloroquine?

A

Chloroquine susceptibility

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16
Q

Doxycycline should be taken 1-2 ___ before traveling and for ___ weeks after traveling

A

1-2 days before traveling and for 4 weeks after traveling

17
Q

Doxycycline is a ___ medication

A

daily medication

18
Q

Which malaria medication should not be used by pregnant women or children <8 years old?

A

Doxycycline

19
Q

Which malaria medication causes an increased risk of sun sensitivity?

A

Doxycycline

20
Q

Which malaria medication can cause an upset stomach and should be swallowed completely with a full glass of water in order to prevent esophageal damage?

A

Doxycycline

21
Q

Which malaria medication is highly controversial due to its psychiatric side effects?

A

Mefloquine

22
Q

Mefloquine should be taken 1-2 ___ before traveling and for ___ weeks after traveling

A

1-2 weeks before traveling and for 4 weeks after traveling

23
Q

Mefloquine is a weekly medicine (T/F)

A

True

24
Q

Which malaria medications are okay in pregnancy?

A

Mefloquine and chloroquine

25
Q

Which malaria medications are good for short trips?

A

atovaquone/proguanil & primaquine

26
Q

Which malaria medications are not good for last minute travelers?

A

chloroquine, mefloquine

27
Q

___ is commonly used to prevent P. vivax after return from travel

A

Primaquine

28
Q

Primaquine should be taken 1-2 ___ before traveling, daily during travel, and for ___ days after traveling

A

1-2 days before traveling, daily during travel, and for 7 days after traveling

29
Q

Primaquine is okay to use in pregnancy (T/F)

A

False

30
Q

What malaria medicine is preferred in P. falciparum in areas with chloroquine resistance?

A

Artemether-lumefantrine (Coartem)

31
Q

For severe malaria, IV artesunate is first line (T/F)

A

True

32
Q

Artemether-lumefantrine (Coartem) or atovaquone-progunail or quinine or mefloquine can be given for severe malaria until the IV artesunate arrives (T/F)

A

True

33
Q

Rickettsia reckettsii causes Rocky Mountain Spotted Fever (T/F)

A

True

34
Q

The appearance of a rash is diagnostic for RMSF and a reliable symptom (T/F)

A

False, rash may/may not appear, can be helpful in diagnosing but not something you can rely on

35
Q

RMSF rash can spread to the trunk and be on the palms and soles of feet (T/F)

A

True

36
Q

What STI does the RMSF rash remind you of?

A

Secondary syphilis! (rash appears on body, palms, and soles of feet) but in syphilis, the rash goes away

37
Q

Empiric treatment for RMSF is

A

Doxycycline

38
Q

RMSF is the only case you do not have to worry about age for giving doxycycline (T/F)

A

True, can be given in children <8 years because need to treat empirically early

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