Malaria & RMSF Flashcards
The most worrisome parasite for malaria is plasmodium _____
falciparum
In which stage do people get sick from malaria, liver or blood?
Blood
The incubation period for malaria can range from __-30 days
7-30 days
P. ___ and P. ____ may be in dormant stages for months and have delayed symptoms by weeks to months
P. ovale and P. vivax
What needs to be tested for when being considered for taking primaquine?
glucose-6-phosphate dehydrogenase (G6PD) - levels should be positive if taking primaquine
Atovaquone/Proguanil should be taken 1-2 ___ before travel and for ___ days after traveling
1-2 days before travel and for 7 days after traveling
Atovaquone/Proguanil is a once daily medication (T/F)
True
Which malaria medication should be avoided in pregnancy and severe renal impairment?
Atovaquone/Proguanil
Are pediatric tablets available for atovaquone/proguanil?
Yes
Chloroquine should be taken 1-2 ____ before traveling and for ____ weeks after traveling
1-2 weeks before traveling and for 4 weeks after traveling
Chloroquine is a daily medication (T/F)
False, weekly medication
Patients taking ______ chronically may not need to take chloroquine
hydroxycholorquine
Chloroquine is good for short trips (T/F)
False, good for long trips due to weekly dose
Which malaria medication can exacerbate psoriasis?
Chloroquine
What needs to be checked before starting chloroquine?
Chloroquine susceptibility
Doxycycline should be taken 1-2 ___ before traveling and for ___ weeks after traveling
1-2 days before traveling and for 4 weeks after traveling
Doxycycline is a ___ medication
daily medication
Which malaria medication should not be used by pregnant women or children <8 years old?
Doxycycline
Which malaria medication causes an increased risk of sun sensitivity?
Doxycycline
Which malaria medication can cause an upset stomach and should be swallowed completely with a full glass of water in order to prevent esophageal damage?
Doxycycline
Which malaria medication is highly controversial due to its psychiatric side effects?
Mefloquine
Mefloquine should be taken 1-2 ___ before traveling and for ___ weeks after traveling
1-2 weeks before traveling and for 4 weeks after traveling
Mefloquine is a weekly medicine (T/F)
True
Which malaria medications are okay in pregnancy?
Mefloquine and chloroquine
Which malaria medications are good for short trips?
atovaquone/proguanil & primaquine
Which malaria medications are not good for last minute travelers?
chloroquine, mefloquine
___ is commonly used to prevent P. vivax after return from travel
Primaquine
Primaquine should be taken 1-2 ___ before traveling, daily during travel, and for ___ days after traveling
1-2 days before traveling, daily during travel, and for 7 days after traveling
Primaquine is okay to use in pregnancy (T/F)
False
What malaria medicine is preferred in P. falciparum in areas with chloroquine resistance?
Artemether-lumefantrine (Coartem)
For severe malaria, IV artesunate is first line (T/F)
True
Artemether-lumefantrine (Coartem) or atovaquone-progunail or quinine or mefloquine can be given for severe malaria until the IV artesunate arrives (T/F)
True
Rickettsia reckettsii causes Rocky Mountain Spotted Fever (T/F)
True
The appearance of a rash is diagnostic for RMSF and a reliable symptom (T/F)
False, rash may/may not appear, can be helpful in diagnosing but not something you can rely on
RMSF rash can spread to the trunk and be on the palms and soles of feet (T/F)
True
What STI does the RMSF rash remind you of?
Secondary syphilis! (rash appears on body, palms, and soles of feet) but in syphilis, the rash goes away
Empiric treatment for RMSF is
Doxycycline
RMSF is the only case you do not have to worry about age for giving doxycycline (T/F)
True, can be given in children <8 years because need to treat empirically early
