Malaria- mosquito interactions Flashcards
Name the 4 phases to bloodfeeding?
- Exploratory phase 2. Probing - stylets inserted, saliva discharged 3. Imbibing - engorging, pre-diuresis occurs 4. Withdrawal
What does a female salivary gland look like?
What is apyrase and its function?
ATP diphosphohdrolase hydrolyses ATP and ADP to AMP and inorganic P It blocks ADP-induced platelet aggregation and promotes haematoma formation
Can you identify all the structures in the midgut theres 14.
Name some enzymes excreted in response to a bloodmeal?
Trypsins, chymotrypsin, aminopeptidase and carboxylase
What does bloodfeeding initiate?
Bloodfeeding initiates a gonotrophic cycle.
What is vitellogenesis?
Fat body goes into the haemolymph, and synthesised into vitellogenin and then into the ovaries as vitellin.
Incorporation of vitellogenin into the ovary?
Vitellogenin passes between the cells of the follicular epithelium, Vg is taken up by receptor mediated endocytosis and fuses with yolk bodies to become crystalline vitellin
What is the egg batch dependent on?
Blood meal size
What is optimum survival strategy for plasmodium?
Oocysts and sporozoites
What changes in plasmodium infected Aedes. Aegypti?
The apyrase content of salivary glands is reduced. Host haemostats is not inhibited.
Inside the midgut what happens to NO?
What can the plasmodium effect?
The plasmodium can effect the vitellogenin expression and therefore the egg production.
When parasites invade, the yolk protein is reduced by how many hours post infection
48hrs
When oocysts are present what is reduced?
Vitellin
