Major CXC Chemokines

Question 1

CXCL8

Answer 1

Original name: IL-8
Chemokine Receptor: CXCR1, CXCR-2
Major Function: Neutrophil recruitment

Question 2

CXCL10

Answer 2

Original name: IP-10
Chemokine Receptor: CXCR3, CXCR3B
Major Function: Effector T cell recruitment

Question 3

CXCL12

Answer 3

Original name: SDF-1alphaß
Chemokine Receptor: CXCR4
Major Function: Homing naive B cells to LNs

Question 4

CXCL13

Answer 4

Original name: BCA-1
Chemokine Receptor: CXCR5
Major Function: B cell migration into follicles; T follicular helper cell migration into follicles