Macromolecules Flashcards
What is the majority of a molecule made of?
Proteins
What’s the phenomenon that happens when 2 monomers react together?
Condensation
What is condensation/dehydration?
It’s when 2 monomers react with one another and one loses an H and the other loses an OH (basically water is removed)
What’s the reverse reaction of condensation?
Hydrolysis
What are proteins made of?
Amino acids
Why is folding so important in proteins?
Folding helps create new bonds, therefore make a bigger molecule
What are the 6 ways amino acids are classified?
- 5 have charged hydrophilic side chains
- 5 have uncharged hydrophilic (polar) side chains
- 7 have hydrophobic (nonpolar) side chains
- Cysteine has a terminal disulfide (—S—S—)
- Glycine has a hydrogen atom as the R group
- Proline has a modified amino group that forms a covalent bond with the R group, forming a ring
What differentiates proline from the other exceptions?
It forms a ring, that includes the amino group
What are the bonds that keep amino acids together?
Peptide bonds
What are the common secondary structures of proteins?
- α-helix (alpha-helix)
- β-pleated sheet (beta-pleated sheet)
What is a α-helix?
- one single strand
- right-handed coil
- held together by H-bonds
What is a β-pleated sheet?
-A single strand that lies parallel to each other and that is pleated
What is a tertiary structure?
One peptide chain that is held together by
- H-bonds
- Disulfide bridges
- van Der waals bonds
- ionic bonds
- aggregation of hydrophobic side chains
What is a primary structure?
A loose strand of peptide bonds
What can affect the shape of a protein?
- changes in temp.
- changes in pH
- changes in salt concentration
- changes in oxidation or reduction conditions
What are chaperonins for?
Control the folding of proteins
What are carbohydrates?
- First source of energy
-C molecules with H groups or hydroxyl groups
What are the 4 major categories of carbohydrates?
- Monosaccharides
- Disaccharides
- Oligosaccharides
- Polysaccharides
What bond keeps monosaccharides together?
Glycocidic bonds
What are the types of monosaccharides (that I need to know)?
- Pentoses: includes ribose and deoxyribose
- Hexoses: includes glucose
What is the ratio of carbon, hydrogen, and oxygen in a carbohydrate?
1 C:2 H:1 O
What is the difference between ribose and deoxyribose?
Ribose has an O bonded to its H but deoxyribose doesn’t
Name 2 Disaccharides.
Sucrose and lactose
What is the job of oligosaccharides?
- Are on cells and act as recognition signals
- The ABO blood types owe their specificity to them
Which glucose form is more stable?
Ring form
What are the 3 types of polysaccharides?
- Starch: Storage for glucose in plants
- Glycogen: Storage for glucose in animals
- Cellulose (fiber): very stable, good for structure components in plants
What does hydrolyze mean?
Breaking a molecule