Mac 8: End Flashcards
Which type of mutation substitutes one amino acid for another?
- Antisense Mutation
- Nonsense Mutation
- Sense Mutation
- Missense Mutation
-Missense Mutation
Which statement is true of “Pseudogenes”?
- Can be transcribed and translated
- Maybe transcribed but not translated
- Rare human gene
- Can cause hemophilia A
-May be transcribed but not translated
A point mutation alters?
- Centromere
- A chromosome tip
- A single base
- Oocyte
-A single base
____ is a change in a gene’s nucleotide base sequence that is rare in a population and can cause a mutant phenotype.
- Cell Division
- Sensitization
- Mutation
- DNA Replication
-Mutation
This type of mutation originates in meiosis, affects all cells of an individual, and can be transmitted to the next generation in gametes.
- Somatic Mutation
- Spermline Mutation
- Germline Mutation
- Direct Mutation
-Germline Mutation
Mutations are more likely to occur in repeated DNA sequences because?
- The repeats hold into the replication enzymes, causing base mismatches
- Bases in the strand can form base pairs, generating loops that interfere with replication and repair enzymes
- The repeats attract and bind to mutagens, increasing the mutation rate
- These bases are unstable
-Bases in the strand can form base pairs, generating loops that interfere with replication and repair enzymes.
An enzyme that joins Okazaki fragments?
- RNA Primase
- RNA Polymerase
- DNA Polymerase
- DNA Ligase
-DNA Ligase
Which of the following statements best describes a mutagen?
- Chemicals or radiation that delete, substitute, or add bases.
- Are expressed only in response to certain environmental triggers
- Results when a duplicate of a gene mutates
- None of the choice
-Chemicals or radiation that delete, substitute, or add bases.
Which among the following results from substitution of the amino acid valine for the glutamic acid that is normally the sixth amino acid in the beta globin polypeptide chain?
- Chronic Granulomatous Disease
- Job’s Syndrome
- Thalassemia
- Sickle Cell Disease
-Sickle Cell Disease
True or False
A somatic mutation originates in meiosis, affects all cells of an individual, and can be transmitted to the next generation in gametes.
-False (Mitosis)
True or False
A somatic mutation originates in mitosis and affects a subset of cells.
-True
In this form of DNA repair, enzymes detect loops and bulges in newly replicated DNA that indicate mispairing.
- Photoreactivation
- Nonsense Repair
- Mismatch Repair
- Base Nucleotide Repair
-Mismatch Repair
A nonfunctional gene near a similar but functional gene is called?
- Phenocopy
- Pseudogenes
- Expanded Gene
- Transposons
-Pseudogenes
Which metaphors correctly compare chromatin remodeling and microRNA function?
- A hammer and nail
- An activator and a repressor
- An on/off switch and a dimmer switch
- An elevator and a submarine
-An on/off switch and a dimmer switch
Ionizing radiation alters DNA sequence by what?
- Deleting Bases
- Removing nitrogen from the bases
- Reversing replication forks
- Breaking the sugar-phosphate backbone
-Breaking the sugar-phosphate backbone
