M3 FGDSRDRS Flashcards

1
Q

Three phases of Cell growth

A

Hyperplasia
Hyperplasia + Hypertrophy
Hypertrophy

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2
Q

Hyperplasia + Hypertrophy. What weeks AOG?

A

Phase of cell growth at 17-32 weeks AOG.

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3
Q

Determinants of hyperplasia

A

Fetal genome

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4
Q
Determinants of hypertrophy EXCEPT
A. Environmental
b. Nutritional
c. Hormonal
d. Fetal Genome
A

D

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5
Q

IUGR is best diagnosed

a. first 16 weeks
b. 17-32 weeks
c. after 32 weeks
d. Any time

A

C

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6
Q

True about symmetrical IUGR EXCEPT

a. Reduced head and body size
b. usually occurs due to placental insufficiency from hypertension
c. least likely due to infection
d. Results in decreased cell number and size

A

B and C

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7
Q

True about asymmetrical IUGR

a. reduced head and body size
b. usually occurs in infections
c. due to late pregnancy insult
d. decreased cell number and size

A

C.

A. reduced body size
B, C late pregnancy insult (placental insufficiency from hypertension)
D. Decreased cell size only

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8
Q

The following are risk factors for IUGR EXCEPT

a. constitutionally small mother
b. poor maternal nutrition
c. social deprivation
d. CMV
e. NOTA

A

E;

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9
Q

The ff are risk factors for IUGR EXCEPT

a. Chorioangioma
b. Preeclampsia
c. APS
d. NOTA

A

D

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10
Q

Most common abnormal sonographic finding in IUGR

A

Abdominal Circumference

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11
Q

Prophylaxis in early gestation is done with what medication?

A

Low dose aspirin (effectively only in 10% cases)

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12
Q

What is the management for IUGR >/= 34 weeks with reassuring FHR

A

Vaginal delivery

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13
Q

What is the management for IUGR >/= 34 weeks with nonreassuring FHR

A

CS

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14
Q

What is the management for IUGR <34 weeks

A
Observation and monitoring until fetal maturity is attained
Qualifications:
-normal fetus
-normal AFI
-normal fetal surveillance
-fetal growth continues
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15
Q

Definition of macrosomia

A

fetus weighing >4,000 (GDM) - >4,500 (nonGDM)

or 4250 ba? verify

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16
Q

Least likely to be risk factor for macrosomia

a. Obesity
b. DM type 2
c. Nulliparity
d. Advance maternal age
e. previous macrosomic infant

A

C. multiparity

17
Q

What is the major concern for trial of labor in macrosomic patients?

A

Possible shoulder dystocia

18
Q

In the 3 phases of fetal growth, the initial phase of hyperplasia characterized by rapid increase in cell number occurs in the first ___ weeks

A

6 weeks

19
Q

Second phase of fetal growth extends up to ___ weeks includes both cellular hyperplasia and hypertrophy

A

32 weeks

20
Q

The third phase of fetal growth occurs after ___ weeks and is characterized by cellular hypertrophy

A

32 weeks

21
Q

Phase of fetal growth where most fetal fat and glycogen are accumulated

a. Initial phase
b. Second phase
c. Third phase
d. NOTA

A

C

22
Q

Correspndoing fetal growth at 15 weeks AOG

a. 4g/day
b. 5g/day
c. 10g/day
d. 20g/day

A

B

23
Q

Correspndoing fetal growth at 24 weeks AOG

a. 5-10g/day
b. 15-20g/day
c. 25-30g/day
d. 30-35g/day

A

B

24
Q

Correspndoing fetal growth at 34 weeks AOG

a. 20-25g/day
b. 30-35g/day
c. 40-45g/day
d. 45-50g/day

A

B

25
Q

True about growth restriction

a. only given to very low birthweight newborns
b. No increase in risk for neonatal mortality
c. Symmetrical growth restriction is better than asymmetrical growth restriction
d. NOTA

A

D

A. Low birthweight
B. Increase risk for neonatal death (especially those with symmetrical growth restriction)
C. Symmetrical is worse

26
Q

Give 3 maternal risk factors for SGA fetus

A
Constitutionally small
Poor nutrition
Eating disorders
Poor gestational weight gain
Soical deprivation
27
Q

True about fetal growth restriction

a. Vascular and Renal disease can cause restricted fetal growth
b. Pregestational DM can cause fetal growth restriction
c. Acquired anemia does not restrict fetal growth
d. AOTA

A

D

28
Q

Some drugs with teratogenic and fetal effects exert—or continue to exert—fetal effects after embryogenesis ends at _____ Examples include anticonvulsants and antineoplastic agents

A

8 weeks