M1, S4, Integumentary System Flashcards
A precursor form of which vitamin is produced in the skin?
Vitamin D
As cells of the outer surface of the epidermis are continually being sloughed off, some cells in the stratum ______ (the bottom layer) of the epidermis divide continuously, replenishing the epidermis.
basale
What are the two sub-layers of the dermis?
- Papillary region
2. Reticular region
The reticular region usually constitutes approximately __% of the dermis.
80%
______ helps to protect the skin and underlying tissue from harmful UV radiation
Melanin
What are the three pigments that contribute towards skin color?
Melanin, carotine, hemoglobin
Carotene is a precursor to vitamin __.
A
Which of the following cell types are usually found in the epidermis?
- keratinocytes
- melanocytes
- erythrocytes
- Langerhans cells
- T cells
- keratinocytes
- melanocytes
- Langerhans cells
Which of the following is the most significant determinant of skin color?
- location of melanocytes
- number of melanocytes
- amount of melanocytes
-AMOUNT of melanocytes
Cells multiply at the basement membrane and move toward the surface, becoming increasingly __________. As they move away from the nutrients of the dermis, they die and flake away on reaching the surface.
keratinized
Approximately 90% of epidermal cells are ___________.
keratinocytes.
These cells are part of the immune system and can recognize foreign microbes, engulf and destroy them, and present their antigens to the immune system for further action.
Langerhans cells
________ cells are found at the border between the epidermis and the dermal layer. They have small dendrites that protrude in between nearby keratinocytes in the stratum spinosum.
Merkel cells
The most superficial layer of the epidermis, consisting of 20-30 layers of dead keratinocytes.
Stratum corneum
A single layer of cuboidal-shaped cells on a ______ membrane. This layer contains stem cells, keratinocytes, and melanocytes. It is also sometimes called the stratum germinativum , due to its role in cell germination, i.e., new skin cells are produced at the basal membrane pushing the older cells towards the surface.
basal
In which of the following locations is the stratum lucidium found?
- armpits
- groin
- soles of the feet
- fingertips
- chin
- soles of the feet
- fingertips
Skin with hair is commonly referred to as ____ skin
thin
Hairless skin is often called _____ skin.
thick
________ growth factors are associated with the overall regulation of skin growth.
Epidermal
_______ strengthens the cells, while ________ adhere the cells to one another and are responsible for the waterproof properties of skin.
Keratin, glycolipids
What is the name of the molecule that is produced by lamellar granules in the stratum granulosum?
Glycolipid
Which of the following epidermal strata contains the most live cells?
Stratum basale