M1 Introduction to Neuroscience Flashcards
the study of the development, chemistry, structure, function,
and pathology of the nervous system.
Neuroscience
This primarily functions to receive sensory stimuli and transmit them to the different organs of the body.
Nervous System
This includes multiple levels of analysis: Molecular, Cellular, Systems, Behavioural, and Cognitive.
Nervous system
investigates the chemistry and physics involved in neural function.
Molecular Neuroscience
distinguishes different types of cells in the nervous system and how each cell type functions.
Cellular Neuroscience
investigates groups of neurons that perform a common function.
Systems Neuroscience
studies the different factors interacting to influence human behaviour.
Behavioural Neuroscience
uncovers the way individuals learn, plan, think, and use their memory and language.
Cognitive Neuroscience
divide the right and left sides of the brain into two equal parts.
Sagittal Plane
Divides the body into an upper (superior) section and a lower (inferior) section.
Transverse
divides the brain into a front (anterior) section and a back (posterior) section.
Frontal Plane
composed of axons, projections of nerve cells that usually convey information away from the cell body, and myelin (an insulating layer of cells that wraps around the axons).
White Matter
It is called a bundle of myelinated axons that travel together in the central nervous system.
tract, lemniscus, fasciculus, column, peduncle,or capsule.
A bundle of myelinated axons that travel together in the central nervous system is called a tract, lemniscus, fasciculus, column, peduncle,or capsule.
White Matter
appears gray and contains primarily neuron cell bodies
Gray Matter
These are groups of cell bodies in the peripheral nervous system
Ganglia
In the central nervous system, groups of cell bodies
are most frequently. These are called?
Nuclei
What is the Gray matter on the surface of the brain?
Cortex
3 Main Cell Layers in the Embryo
Endoderm, Mesoderm, Ectoderm.
It is the massive reorganization of the embryo from a simple spherical ball of cells, the _______, into multilayered organisms.
Blastula, Gastrulation
It is the formation of neural tube, which gives rise to the brain and spinal cord.
Neurulation
What Developmental stage in Utero?
- Conception to 2 weeks
- Formation of Blastocyst
- Gastrulation occurs during the end of the 2nd week
Preembryonic Stage
What Developmental stage in Utero?
- 2nd to end of 8th week
- Formation of Organs
Embryonic Stage
What Developmental stage in Utero?
- End of 8th week until birth
- Nervous systems develop more fully, and myelination begins
Fetal Stage
What is the Primary division of forebrain vesicle?
Prosencephalon
What are the subdivision of forebrain?
Telencephalon and Diencephalon
What are the adult structures of the forebrain vesicle?
Telen: Cerebral hemisphere, basal ganglia, hippocampus
Dien: Thalamus, hypothalamus, pineal body, infundibulum.
What is the primary division of the midbrain vesicle?
Mesencephalon
What is the subdivision of Mesencephalon?
Mesencephalon
What are the adult structures of the midbrain vesicle?
Tectum, tegmentum, crus cerebri.
What is the primary division of the hindbrain vesicle?
Rhombencephalon
What are the subdivisions of the hindbrain vesicle?
Metencephalon and Myelencephalon
What are the adult structures of the hindbrain vesicle?
Meten: Pons, Cerebellum
Myelen: Medulla Oblongata
The 2 concentric layers of the Neural Tube
Mantle layer and Marginal layer
It is the inner wall and contains cell bodies and will become gray matter.
Mantle layer
It is the outer wall that contains processes of cells and will develop into white matter, consisting of axons and glial cells.
Marginal layer
It is a group of muscles derived from one somite and innervated by a single spinal nerve.
Myotome
It processes sensory information.
Dorsal Horn
It forms peripheral sensory neurons, myelin cells,
autonomic neurons, and endocrine organs.
Neural Crest
2 processes of the neural crest
- connects to the spinal cord
- inervates the dermatome
Are spherical cell clusters from the mesoderm.
Somites
It causes bulging in the surface of the embryo.
Somites
Contains the vertebrae and the skull.
Scleratome
Contains the skeletal muscles.
Myotome
Contains the dermis.
Dermatome
What are the functional divisions?
Autonomic, Somatic, and Somatosensory Nervous System
Consists the brain and the spinal cord.
Central Nervous System
Divided into: Cerebrum and Diencephalon
Brain
The most massive part of the brain.
Forebrain: Cerebrum
Connects two cerebral hemispheres.
Corpus Callosum
It is the Deep cleft separating the hemisphere.
Longitudinal fissure
Are the Folds or elevation in the cerebral cortex.
Gyrus
Are grooves and fissures along the cerebral cortex.
Sulcus
Thinking, memory, behaviour, and movement.
Frontal lobe
Hearing, learning, and feeling.
Temporal lobe
Breathing, heart rate, and temperature.
Brainstem
Language and touch.
Parietal lobe
Sight
Occipital lobe
Balance and coordination
Cerebellum
The site for reasoning, language, communication, intelligence, and personality.
Gray matter and Cerebral cortex.
The axon that connects the cerebral cortex with the other
CNS areas.
White Matter
- Higher order functions
- The site for reasoning, language, communication,
intelligence, and personality
Gray Matter or Cerebral cortex
- These are masses of gray matter within the white matter.
- Responsible for social and goal-oriented behavior, movement and emotions.
- Execute smooth movement
Basal Ganglia or Nuclei
Process emotions and motivation.
Amygdala
Process memory
Hippocampus
- The largest egg-shaped mass of gray matter forms the major part of the diencephalon.
- Important relay station for passing sensory information.
Thalamus
- 0.3% of the brain
- Controls the autonomic nervous system and endocrine system.
Hypothalamus
Holds the Pineal Body (influences the secretion of other endocrine glands)
Epithalamus
Part of the neural circuit that controls the movement.
Subthalamus
Connects the third and fourth ventricles.
Cerebral Aqueduct
Contains many nuclei and bundle of ascending and descending nerve fibers.
Cerebral Aqueduct
a large number of transverse fibers on its anterior aspect connecting the two cerebellar hemispheres.
Bridge
Many nuclei and ascending and descending nerve fibers.
Pons
- The largest part of the hindbrain
- 2 hemispheres are connected by a vermis.
- Consist of Superior/Middle/Inferior
- Cerebellar Peduncles.
- Cerebellar Cortex
- Thrown in folds or foil.
Functions: Posture, Balance and Coordination (POBACO)
Cerebellum
- Connected to the third ventricle
via cerebral aqueduct. - Continuous to the central canal of
the spinal cord.
Hindbrain: Fourth ventricle
Spinal cord: Cell bodies of neurons
Gray matter
Axons and Myelin
White Matter
PNS: 2 types of axons
Afferent and Efferent axons
PNS divides into?
Somatic & Autonomic Nervous System
- regulates certain body processes, such as blood pressure and the rate of breathing regulates
Autonomic NS
2 types of Autonomic NS
Sympathetic (fight or flight)
Parasympathetic
- allows you to move and control muscles throughout your body.
- involves things you can consciously sense and do.
Somatic Nervous System
2 main functions of Somatic NS
Sensory Input and Movement Control
contains the brain and its surrounding meninges, portions of the cranial nerves, arteries, veins, and venous sinuses.
Cranial Cavity
is the upper part of the cranium; where sagittal, coronal, and lambdoid sutures are found.
Vault of the skull
- is the lowest part of the cranium;
- It has three cranial fossae: anterior, middle, and posterior
Base of the skull
lodges the frontal lobes of the cerebral hemisphere
Anterior Cranial Fossa
Boundaries of Anterior Cranial Fossa
ant: inner surface of frontal bone
post: lesser wing of sphenoid
floor: orbital plates of frontal bone
- upper surface supports the olfactory bulbs
- small perforations are for the olfactory nerves
Cribriform Plate
houses the temporal lobes and pituitary gland
Middle Cranial Fossa
- found in the lesser wing of sphenoid
- passage for optic nerve, opthalamic artery
Optic Canal
- Between the lesser and greater wings of sphenoid
- passage for lacrimal, frontal, trochlear, oculomotor, nasociliary, and abducent nerves; superior opthalamic vein
Superior Orbital Fissure
- found in the greater wing of sphenoid
- passage for maxillary division of the trigeminal nerve
Foramen Rotundum
- found in the greater wing of sphenoid
- passage for mandibular division of the trigeminal nerve
Foramen Ovale
- found in the greater wing of sphenoid
- passage for middle meningeal artery
Foramen Spinosum
- found between the petrous part of the temporal and sphenoid
- passage for internal carotid artery
Foramen Lacerum
- lodges the cerebellum, pons, and medulla oblongata
Posterior Cranial Fossa
Boundaries of Posterior Cranial Fossa
Ant: superior border of the temporal bone
post: internal surface of occipital bone
roof: tentorium cerebelli
- found in the occipital bone
- passage for medulla oblongata, spinal part of accessory nerve, and right and left vertebral arteries
Foramen Magnum
- found in the occipital bone
- passage for hypoglossal nerve
Hypoglossal Canal
- between the petrous part of the temporal and condylar part of the occipital bone
- passage for glossopharyngeal, vagus, ans accessory
- nerves: sigmoid sinus becomes internal jugular vein
Jugular foramen
- found in the petrous part of the temporal bone
- passage for vestibulocochlear and facial nerves
Internal Acoustic Meatus
outermost and strongest covering of the brain
Dura Mater
2 layers of Dura Mater
Endosteal and Meningeal layers
does not extend through the foramen magnum; becomes part of the skull
Endosteal Layer
dura mater proper; continuous through the foramen magnum with the dura mater of the spinal cord
Meningeal layer
a sickle shaped fold of dura mater between the cerebral hemispheres
Falx Cerebri
a small sickle shaped fold of dura mater between the 2 cerebellar hemispheres
Falx cerebelli
a crescent shaped fold of dura mater that roofs over the posterior cranial fossa
Tentorium Cerebelli
- A delicate, impermeable membrane lies between the pia mater internally and the dura mater externally.
- separated from the dura by the subdural space, and from the pia by the subarachnoid space, which is filled with cerebrospinal fluid (CSF)
Arachnoid matter
- Removes waste products associated with neuronal activity
- Provides a fluid medium in which the brain floats, protecting the brain from trauma
Arachnoid Matter
- innermost layer
- a vascular membrane that closely invests the brain, covering the gyri and descending into the deepest sulci
- extends over the cranial nerves and fuses with their epineurium
Pia mater