Lysosome

Question 1

What enzyme pumps H+ Out of a lysosome ?

Answer 1

V-TYPE ATPase

Question 2

Mucopolysaccharidoses disease ?

Answer 2

HURLER SYNDROME
HUNTER SYNDROME

Question 3

Mucolipidoses diseases.?

Answer 3

I-CELL (2) (M6PTAG)
Pseudo Hurler

Question 4

Sphongolipidoses?

Answer 4

TAY SACH
METACHROMATIC LEUKODYSTROPHY

Question 5

Leukodystrophies ?

Answer 5

Chediak-higashi syndrome

Question 6

Disease with
AR
CORNEAL CLOUDING
HEPATOSPLENOMEGALY
LESS GROWTH
DEATH IN 10 YEARS
DEFICIENCY OF ALPHA-L-IDURONIDASE

Answer 6

HURLER SYNDROME

Question 7

DISEASE WITH

X-LINKED
DEF OF IDRUNATE SULFATASE
DERMATAN AND HEPARIN ACCUMULATION

Answer 7

HUNTER SYNDROME

MUCOPOLYSACCHARIDOSES

Question 8

Disease with

AR
CHERRY RED MACULA
MUSCLE WEAKNESS
NEURO DEGENERATION
ACCUMULATION OF GM2 GANGLIOSIDE

Answer 8

TAY SACH
(SPINGOLIPIDOSES)

Question 9

Disease with

AR
COGNITIVE DECLINE
PARALYSIS
MYELIN DEGENERATION

Answer 9

METACHROMATIC LEUKODYSTROPHIE
(SPINGOLIPIDOSES)

ARYL SULFATASE A DEFECT

Question 10

Disease with
AR
ROUGH FACIAL FEATURE
RESTRICTED JOINT MOVEMENT
LIFE EXPECTANCY LESS THAN 10
DEF IN GOLGI-N-ACETYLGLUCOSAMINE (NAG)

Answer 10

I CELL
M6P TAG
(MUCOLIPIDOSES 2)

Question 11

AR
Milder form of I CELL
LATE ONSET

Answer 11

PSEUDO HURLER