Lymphomas Flashcards

1
Q

Assessment of a Patient with lymphoma shows involvement of a single node,
What is the stage of this lymphoma?

A

Stage I

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2
Q

Assessment of a Patient with lymphoma shows involvement of >1 nodal groups on same side of diaphragm,
What is the stage of this lymphoma?

A

Stage II

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3
Q

Assessment of a Patient with lymphoma shows involvement of nodes on both sides of diaphragm,
What is the stage of this lymphoma?

A

Stage III

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4
Q

Assessment of a Patient with lymphoma shows dissemination to bone marrow
What is the stage of this lymphoma?

A

Stage IV

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5
Q

Diagnosis of classical hodgkin lymphoma is based on presence of……. Cells

A

Reed sternberg

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6
Q

Treatment of stage IA-IIA classical hodgkin lymphoma

A

ABVD chemo x3 followed by consolidation therapy

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7
Q

Treatment of stage IIB-IV Classical hodgkin lymphoma

A

. ABVD 6-8 COURSES
. Consolidation tx

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8
Q

Tx of stage I follicular lymphoma

A

Involved field radiotherapy

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9
Q

Tx of stage II-IV follicular lymphoma

A

If Asymptomatic: watch and wait
If symptomatic:
=chemotherapy RCVP
=low intensity allograft

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10
Q

Tx of diffuse large B Cell lymphoma

A

. Stage I (non bulky): R-CHOP followed by involved field radiotherapy
. All other pts : treat as for advanced cases, R-CHOP

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11
Q

T cells in parafollicular areas in lymphnodes are positive for CD…..

A

CD 3

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12
Q

Germinal centrers in lymphnodes show high levels of……

A

Ki67

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13
Q

In lymphnodes, Follicular areas rich in B cells are positive for CD…..

A

CD20

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14
Q

Most of ALL cases stain for……….. Which is an enzyme specifically expressed in pre-B and pre-T cells.

A

Tdt (terminal deoxynucleotidyl transferase)

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15
Q

Microscopy of a biopsy from a tumor in the jaws of a 5 yr old child from west africa shows starry sky appearance.
What is the diagnosis?

A

Burkitt’s Lymphoma

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16
Q

Germinal center B cell marker in a LN is CD….

A

CD 10

17
Q

CD markers of classic Hodgkins lymphoma

A

CD 15 and CD30
Highlighting Reed sternberg cells

18
Q

In NLPHL, Lymphohistiocytic reed sternberg cells express….. Cell markers

A

B cell markers (CD20)

19
Q

Follicular lymphoma expresses Which CD MARKERS?

A

. B cell marker CD20+ve /CD3-ve
. Germinal cemter B cells marker : CD10 & BCL2