Lymphoma and Myeloma Flashcards
what is lymphoma?
cancer of cells in the lymphatic system
cells in lymph nodes, spleen, thymus are replaced by malignant cells
what are the 2 types of lymphoma?
Hodgkin’s and Non-Hodgkin’s lymphoma
which lymphoma has Reed-Sternberg cells?
Hodgkin’s lymphoma
what is the difference between Hodgkin and Non-Hodgkin lymphoma?
Hodgkin’s spreads nearby and is rarely extra-nodal
Non-Hodgkin’s spreads further away and to extra-nodal sites e.g. skin, brain
name some symptoms extra-nodal spread with non-Hodgkin’s lymphoma
GI: bowel obstruction
bone marrow: reduced RBC, WBC, platelets
spinal cord: compression
treatment of lymphoma?
Rituximab
which type of cancer is associated with EBV?
Hodgkin’s lymphoma
which cells are affected in myeloma?
plasma cells in the bone marrow
what is multiple myeloma?
myeloma found in many parts of the bone marrow
what are the characteristic symptoms of multiple myeloma?
CRAB
- hyperCalcaemia
- Renal impairment
- Anaemia
- Bone pain
is myeloma treatable?
no - chronic incurable disease
diagnosis of lymphoma?
lymph node biopsy