Lymphoma and Myeloma Flashcards

1
Q

what is lymphoma?

A

cancer of cells in the lymphatic system

cells in lymph nodes, spleen, thymus are replaced by malignant cells

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2
Q

what are the 2 types of lymphoma?

A

Hodgkin’s and Non-Hodgkin’s lymphoma

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3
Q

which lymphoma has Reed-Sternberg cells?

A

Hodgkin’s lymphoma

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4
Q

what is the difference between Hodgkin and Non-Hodgkin lymphoma?

A

Hodgkin’s spreads nearby and is rarely extra-nodal

Non-Hodgkin’s spreads further away and to extra-nodal sites e.g. skin, brain

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5
Q

name some symptoms extra-nodal spread with non-Hodgkin’s lymphoma

A

GI: bowel obstruction

bone marrow: reduced RBC, WBC, platelets

spinal cord: compression

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6
Q

treatment of lymphoma?

A

Rituximab

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7
Q

which type of cancer is associated with EBV?

A

Hodgkin’s lymphoma

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8
Q

which cells are affected in myeloma?

A

plasma cells in the bone marrow

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9
Q

what is multiple myeloma?

A

myeloma found in many parts of the bone marrow

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10
Q

what are the characteristic symptoms of multiple myeloma?

A

CRAB

  • hyperCalcaemia
  • Renal impairment
  • Anaemia
  • Bone pain
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11
Q

is myeloma treatable?

A

no - chronic incurable disease

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12
Q

diagnosis of lymphoma?

A

lymph node biopsy

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