Breast cancer Flashcards

1
Q

is breast cancer a common cancer?

A

most common female cancer

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2
Q

what are some of the symptoms experienced with breast cancer?

A
breast lump (single, firm, non-tender, immovable)
nipple discharge
nipple inversion
skin changes 
axillary mass
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3
Q

what is done to screen for breast cancer?

A

mammography

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4
Q

what are the risk factors for breast cancer?

A
  • family history
  • oestrogen exposure
  • previous breast cancer
  • older age
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5
Q

what factor is protective against breast cancer?

A

breast feeding

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6
Q

what factors can increase a persons oestrogen exposure?

A

early menarche, late menopause
HRT and oral contraceptive pill
first child >35 years
obesity

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7
Q

what % of cases of breast cancers are associated with BRCA mutations?

A

5%

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8
Q

what is the most common subtype of breast cancer?

A

adenocarcinoma, invasive ductal carcinoma

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9
Q

what are the signs of lymphatic involvement of breast cancer?

A

p’eau d’orange

arm oedema

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10
Q

where does breast cancer commonly spread to in the blood?

A

bones
lungs
liver
brain

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11
Q

how does breast cancer that has spread to bones present?

A

bone pain
increased calcium
fractures

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12
Q

how does breast cancer that has spread to lungs present?

A

dyspnoea

pleural effusion

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13
Q

how does breast cancer that has spread to brain present?

A

headache

seizures

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14
Q

how does breast cancer that has spread to liver present?

A

abdominal pain

hepatic impairment

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15
Q

how often is breast cancer screening done?

A

every 3 years from 50-70

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16
Q

what does a triple assessment involve?

A

clinical evaluation (history and examination)
imaging (ultrasound or mammography)
tissue diagnosis with needle biopsy

17
Q

what are the targeted therapy options for breast cancer?

A

tamoxifen or herceptin

18
Q

what does tamoxifen target?

A

oestrogen positive breast cancer

19
Q

what does herceptin target?

A

HER2 positive breast cancer