lymphoma and leukemia Newman

Question 1

what is the most common cancer in adolesecents

Answer 1

lymphoma

Question 2

HL ___ symptoms

Answer 2

B symptoms
unexplained fever of 39 degrees C (103)
wt loss over 10% total body wt over 6 months
drenching night sweats
fatigue

Question 3

diagnosis of HL

Answer 3

any pt with persistent unexplained LAD unassociated with obvious underlying inflamatory or inectious process should undergo chest radiography to rule out a mediastinal mass before undergoing LN biopsy

Question 4

what accounts for 60% of lymphomas in children and adolescents

Answer 4

NHL

Question 5

inherited or acquired immune deficiencies in NHL

2 diseaese and symptoms of 2nd

Answer 5

SCID
Wiscott-Aldrich syndrome (X-linked recessive)
   recurrent sinopulmonary infection
   eczema
   bleeding

Question 6

NHL that commonly manifests as abdominal or head and neck disease with involvement of the bone marrow or CNS

Answer 6

burkitt lymphoma

Question 7

childhood leukemia pathogenesis

Answer 7

results from malignant transformation and clonal expansion of HSC at early stage of differentiation that are then unable to undergo further maturation

Question 8

what constitiues 97% of all childhood leukemias

Answer 8

acute leukemias