Lymphoma

Question 1

Describe appearance of Reed Sternberg cells

Answer 1

Mirror image nuclei

Question 2

Which specific cells are found in Hodgkin’s

Answer 2

Red Sternberg cells

Question 3

Associations of Hodgkins Lymhpoma

Answer 3

EBV
Familial
LE
Post Tx

Question 4

Describe bimodal distribution of Hodgkin’s Lymphoma

Answer 4

Peak at 15-35yrs

Peak in elderly

Question 5

What is Hodgkins lymphoma split up into

Answer 5

A - no systemic or B symptoms

B - B Symptoms

Question 6

Commonest presentation of Hodgkin’s Lymphoma

Answer 6

Enlarged/non-tender rubbery LN

Question 7

Name the B symptoms

Answer 7

W.t loss
Fever
Night sweats

Question 8

Dx of Hodgkins Lymphoma

Answer 8

Tissue Dx

By LN biopsy

Question 9

Rx for Hodgkins Lymphoma

Answer 9

Combo chemotherapy +/- radiotherapy
Monoclonal antibodies (Anti CD30)
Immunotherapy

Question 10

Which staging system is used for Hodgkin’s Lymphoma

Answer 10

Ann Arbor

Stages from 1-4

Question 11

Describe Ann Arbor I

Answer 11

Single LN involved

Question 12

Describe Ann Arbor II

Answer 12

2 or more LN on the same side of the diaphragm

Question 13

Describe Ann Arbor III

Answer 13

Involvement of LN on both sides of the diaphragm

Question 14

Describe Ann Arbor IV

Answer 14

Spread beyond the LN