Lymphocyte-Plasma Cell Series

Question 1

What WBC is known to recirculate between blood and lymph?

Answer 1

Lymphocyte

Question 2

What are the two primary lymphoid organs?

Answer 2

• Bone Marrow

- Thymus (2 lobed organ behind sternum)

Question 3

What are the two secondary lymphoid organs?

Answer 3

• Lymph Nodes

- Spleen

Question 4

Describe B Lymphocytes

Answer 4

• Derived from the bone marrow
• End cell of B-Cell maturation-plasma cell
• Function in Humoral defense
  
  • Antibody production
  • Immediate hypersensitivity
• Short-lived (

Question 5

Describe T Lymphocytes

Answer 5

• Developed under influence of thymus
• Function in cellular defense
  
  • Defense against intracellular organisms and neoplasms
  • Delayed hypersensitivity (Graft vs. Host Disease)
• Long-lived (months to years)

Question 6

State the major function of the lymphatic system

Answer 6

Collect and dispose of lymph, a watery extravascular fluid of tissues.

Question 7

State four functions of the spleen

Answer 7

1. Filtration
2. Cell Grooming
3. Reservoir
4. Immunity

Question 8

Name the Lymphocyte:

10-20 microns; Scant Cytoplasm, slightly to moderately basophilic; Fine Chromatin; Round to oval nucleus

Answer 8

Lymphoblast

Question 9

Name the Lymphocyte:

9-18 microns; Light blue cytoplasm; slightly clumped chromatin; round or indented nucleus

Answer 9

Prolymphocyte

Question 10

Name the Lymphocyte:
7-18 microns; Scant to moderate cytoplasm, sky-blue, vacuoles may be present; Condensed, clumped, blocky, smudged chromatin; round to oval nucleus, may be slightly indented

Answer 10

Lymphocyte

Question 11

What is the final stage of B-cell maturation?

Answer 11

When a B-Cell is stimulated by antigen, it undergoes mitosis and transforms into a plasma cell line;

• Plasmablast
• Proplasmacyte
• Plasma Cell

Question 12

Define Hof Area

Answer 12

-Clear area next to nucleus