lymphedema Flashcards
lymphatic system (6)
and function
- tonsils - spleen - thymus gland - lymph nodes - lymphatic vessels - peyer’s patches (intestines)
- prevents interstitial edema - assists in the digestion of fats - immunological functions - one way system
lymph nodes
- 600-900
- drain regions
- make WBC
- filter and concentrate fluid
- drain all tissues except for CNS
superficial lymphatic system
- like the roots of a plant
- from the most distant parts of the body to the venous angles
- anatomical variation is common
deep lymphatic system
- thoracic duct drains approx 3/4 of the body
- right lymphatic duct drains approx 1/4 of the body
lymphatic system carrying
and what happens to it?
proteins - cells - water - fats
- eventually lymph fluid returns to the venous system and becomes part of the plasma
- must have healthy heart, lungs, and kidneys to process that fluid!
lymph capillaries
- single cell layer
- no basement membrane
- anchoring filaments
- swinging flaps to prevent backflow
lymphatic transporting vessels
- collectors: basement membranes - muscular walls - valves
2. trunks/ducts: largest vessels - thoracic duct - right lymphatic duct
lymphedema
abnormal accumulation of protein rich fluid in the interstitial spaces
- results in chronic inflammation and reactive fibrosis of the tissues
- progressive
lymphedema: clinical sign
pitting edema
- feels warm and soft - then soft playdough - the silly putty
lymphedema: typical locations
- extremities (uni or bilateral)
- trunk and breasts
- genitals
- intestinal
- head and neck
primary lymphedema
- lymphatic dysplasia
- can be hereditary
- often onset is at menstruation or pregnancy
secondary lymphedema
- lymph node surgery
- radiation therapy
- traumatic injury to vessels or nodes
- surgical scarring
- malignant lymphedemas
stage 0
- latency
- patient is at risk for lymphedema, no visible and/or palpable swelling
- check for subjective complaints
- may use bioelectrical impedance analysis (BIA) to detect changes on affected side
- treatment?
stage 1
- reversible
- visible swelling (may be fluctuating)
- check for subjective complaints
- mainly protein-rich fluid which responds to elevation
- treatment?
stage 2
- spontaneously irreversible
- visible, chronic swelling
- protein-rich fluid and fibrosis
- elevation may provide some relief but will not be very effective
- treatment?
stage 3
- lymphostatic elephantiasis
- visible, chronic swelling
- protein-rich fluid, fibrosis, skin changes and cellulitis
- infections common
- treatment?
usual S&S lymphedema
- onset may be slow or rapid
- progressive
- pitting
- often starts distally (squaring of toes, stemmer’s sign positive, loss of anatomical, asymmetric if bilateral)
- cellulitis is common
- discomfort is common (heaviness, achiness, etc)
- skin changes (later stages: hyperkeratosis, papillomas)
- ulcerations are unusual
- in contrast with venous disease the skin maintains hydration and elasticity for longer in the disease process
hyperkeratosis
over abundance of epidermal thickening with lymphedema
- changes start distally on the limb: hardened tissue, can be moss like, abrasive in advanced presentation
differential dx (9)
- venous insufficiency/obstruction
- congestive heart failure
- hepatic/renal disorders (biliary)
- nutritional disorders
- lipedema
- myxedema (thyroid disease)
- CRPS
- fluid retention symptoms
- immobility/dependency
CHF/cardiac edema
- bilaterally symmetric LE edema
- lacks skin coloring changes compared to CVI
- soft pitting
- reduces with elevation
- shiny skin due to fluctuations in dependent edema
- lower leg or entire leg
- toes usually uninvolved
- dyspnea
- orthopnea
- diuretics helpful