Lymphedema Flashcards
What compromises the lymphatic system?
Lymphatic organs:
- Lymph nodes (600-700 in the body): filtering stations that produce WBC and regulate proteins in the lymph
- Lymph vessels: provide intrinsic contractions 6-10x/minute
- Thymus gland
- Spleen
- Tonsils
- Peyer’s patches
Approximately how many lymph nodes are located in the axillary area?
30-40 lymph nodes
What comprises lymphatic vessels?
- Capillaries
- Pre-collectors
- Collectors
- Trunks
Vessels are all different sizes and carry the lymph differently
What are mechanisms of lymph transportation?
- Intrinsic contraction
- Respiration
- Arterial/venous pulsation
- Skeletal movement
- New lymph creates pressure
Where is 3/4 of the body’s lymph drained?
- Into the left side of the thoracic duct
Which direction to lymph valves go?
- Only one way
- Lymph nodes affect the front and back of the body
What makes up lymph fluid?
- Proteins: 75-100 g of proteins are transported by the lymph vessels per day
- Water
- Cells: RBC, WBC, lymphocytes
- Waste products and other foreign substances
- Fat (instestinal lymph, chyle)
How many liters of lymph does the body transport in one day?
- 2-2.5 L/day
How does fluid move from place to place?
- Through pressure gradients
- Diffusion: movement of fluid from high concentration to low concentration
- Osmosis: passage of fluid through semipermeable membrane
- Ultrafiltration: mechanical pressure separates water from protein and pushes water through membrane
Filtration = resorption and lymph flow
What are physiological factors to consider when treating someone with lymphedema?
- Lymphatic Load (LL): how much water, proteins, cells, etc. normally need to move
- Lymph Time Volume (LTV): amplitude and frequency of intrinsic contractions = lymph load
- Transport Capacity (TC) = Max LTV or 10x LL intact system
- Functional Reserve (FR): difference between TC and LL
What is considered normal in the lymphatic system?
- LL (lymphatic load) < TC (transport capacity)
What is dynamic insufficiency?
- The lymphatic system is overloaded: venous insufficiency, cardiac edema, DVT, etc.
- The lymphatic system is still able to move most proteins after swelling
- LL (lymphatic load) > TC (total capacity)
What is mechanical insufficiency?
- TC (total capacity) = LTV (lymph time volume) and LL (lymphatic load is greater than both)
- Lymphedema always includes mechanical insufficiency
- May be due to surgery, trauma, radiation, etc.
- Body is not capable of moving proteins out
What is combined insufficiency?
- Lymphatic load is high and system is damaged
- May be due to obesity, CVI, lipedema
What is the definition of lymphedema?
- An abnormal collection of protein-rich fluid in the interstitium, which causes chronic inflammation and reactive fibrosis of the affected tissues
- The lymph load (LL) exceeds the total capacity of the system
- Can occur anywhere in the body