Lymphatic System

Question 1

Lymph

Answer 1

Fluid connective tissue kind of like blood

Question 2

Interstitial space/interstitium

Answer 2

Space surrounding tissue cells and is filled with interstitial fluid

Question 3

Lymphocyte locations

Answer 3

Tonsils, spleen, thymus, bone marrow (WBC)

Question 4

Endothelial cells

Answer 4

Cells lining the inner most layer of blood vessels

Question 5

Lymphatic capillaries/terminal lymphatics

Answer 5

• Have fluid entering through overlapping cells that act as one way valve
• The initial location where circulation starts

Question 6

Small lymphatic vessels

Answer 6

Move fluid throughout body

Question 7

Superficial lymphatic

Answer 7

Nodes are located near cervical (neck), axillary (armpits), and inguinal (next to gentian area)

Question 8

Deep lymphatic

Answer 8

Nodes are located near tracheobronchial (trachea), aortic (aorta at the stomach), and iliac (under the belly)

Question 9

Lymphocytes

Answer 9

• Natural killer cells
• T cells (CD8 and CD4)
• B cells (plasma cells)

Question 10

CD8 cytotoxic T cells

Answer 10

Attack foreign cells and infected body cells using cell-mediated immunity

Question 11

CD4 helper T cells

Answer 11

Stimulate T and B cell activity

Question 12

Plasma B cells

Answer 12

Produce antibodies/immunoglobulin/Igs which bind to antigens and mark for destruction AKA humoral immunity

Question 13

Natural killer cells

Answer 13

Attack virally infected cells and cancer cells

Question 14

Lymphocyte production

Answer 14

1) stem cells turn into lymphocyte progenitors
2) L. Progenitors divide into pre B, pre T cells, and NK cells
3) Some pre B cells turn into NK cells
4B) B cell continue development in bone marrow
5B) B cell migrate into blood vessel
4T) T cells leave bone marrow and go to thymus
5T) T cell become either CD8 or CD4

Question 15

Lymphoid tissue

Answer 15

Connective tissues with many lymphocytes

Question 16

Mucosa associated lymphoid tissue (MALT)

Answer 16

Clusters of lymphoid nodules

Question 17

Appendix

Answer 17

Small pocket of cecum and contains large clusters of MALT

Question 18

Peyer’s patches

Answer 18

Lymphatic nodules found in mucosa of ilium

Question 19

Tonsils

Answer 19

Large nodules in walls of pharynx

Question 20

Thymus

Answer 20

• Has two lobes, each with cortex and medulla
• T cells grow in cortex, then go to medulla, then leave to go into circulation
• No immune response or antigen presentation

Question 21

Reticular epithelial cells

Answer 21

• Surround thymus cortex and blood vessels, which maintain barrier
• Secrete thymus hormones that stimulate T cell development

Question 22

Spleen

Answer 22

• Begin immune response, store iron from recycled RBC, remove abnormal blood cells
• cleanse and give immune cells chance to limited
• Red (RBC and macrophages) and white pulp (WBC)