Lymphatic System Flashcards

1
Q

How much interstitial fluid does the lymphatic system collect per day?

A

3L

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2
Q

How much interstitial fluid does the lymphatic system collect per day?

A

3L

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3
Q

Where are there no lymphatics?

A

CNS

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4
Q

What is cellulitis?

A

An infection of the deeper layers of the skin and underlying tissue

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5
Q

What is an ulcer?

A

A break in the continuity of the epithelium

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6
Q

What is MALT?

A

Mucosal associated lymphatic tissue

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7
Q

Name some lymphatic nodules

A

Tonsils, peyers patches, appendix

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8
Q

Name some lymphatic organs

A

Lymph nodes, thymus, spleen

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9
Q

Where in the GI system are there lots of lymphatics?

A

Small bowel particularly the ileum

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10
Q

What are peyers patches?

A

Organised lymphoid nodules (aggregations of GALT)

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11
Q

Where can peyers patches be found?

A

In the ileum

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12
Q

What is lymph node flow aided by?

A

Adjacent skeletal muscle
Adjacent arteries
Pressure changes in thorax

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13
Q

Is the liver part of the lymphatic system?

A

No

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14
Q

Where do the afferent lymphatics arrive to in the LN?

A

Convex surface

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15
Q

How to the efferent lymphatics leave the LN?

A

Hilum

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16
Q

How are lymphatic nodules arranged?

A

Germinal centres and outer cortex

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17
Q

Where are follicular dendritic cells found?

A

Germinal centres

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18
Q

What do dendritic cells cause?

A

Proliferation of B cells

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19
Q

Name some professional APCs?

A

B cells and macrophages

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20
Q

What cells mediate inflammation?

A

Macrophages and neutrophils

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21
Q

What mediates the humoral response?

A

B cells - produce antibodies

22
Q

What cell medicates the cell mediated response?

23
Q

Why do LN swell in response to infection?

A

Germinal centres fill with lymphocytes

24
Q

Roles of the spleen

A

Antigen presentation
Activation of b and t cells
Remove old and abnormal RBC and platelets
Retrieval of iron from RBC

25
What is there a risk of post splenectomy?
Increased risk of infection by encapsulated bacteria | Increased risk of DVT and PE
26
Where is the thymus found?
Superior mediastinum
27
What is the role of the thymus?
Thymic cell education | Maturation of bone marrow derived stem cells into immunocompetent t cells
28
Where are there no lymphatics?
CNS
29
What is cellulitis?
An infection of the deeper layers of the skin and underlying tissue
30
What is an ulcer?
A break in the continuity of the epithelium
31
What is MALT?
Mucosal associated lymphatic tissue
32
Name some lymphatic nodules
Tonsils, peyers patches, appendix
33
Name some lymphatic organs
Lymph nodes, thymus, spleen
34
Where in the GI system are there lots of lymphatics?
Small bowel particularly the ileum
35
What are peyers patches?
Organised lymphoid nodules (aggregations of GALT)
36
Where can peyers patches be found?
In the ileum
37
What is lymph node flow aided by?
Adjacent skeletal muscle Adjacent arteries Pressure changes in thorax
38
Is the liver part of the lymphatic system?
No
39
Where do the afferent lymphatics arrive to in the LN?
Convex surface
40
How to the efferent lymphatics leave the LN?
Hilum
41
How are lymphatic nodules arranged?
Germinal centres and outer cortex
42
Where are follicular dendritic cells found?
Germinal centres
43
What do dendritic cells cause?
Proliferation of B cells
44
Name some professional APCs?
B cells and macrophages
45
What cells mediate inflammation?
Macrophages and neutrophils
46
What mediates the humoral response?
B cells - produce antibodies
47
What cell medicates the cell mediated response?
T cell
48
Why do LN swell in response to infection?
Germinal centres fill with lymphocytes
49
Roles of the spleen
Antigen presentation Activation of b and t cells Remove old and abnormal RBC and platelets Retrieval of iron from RBC
50
What is there a risk of post splenectomy?
Increased risk of infection by encapsulated bacteria | Increased risk of DVT and PE
51
Where is the thymus found?
Superior mediastinum
52
What is the role of the thymus?
Thymic cell education | Maturation of bone marrow derived stem cells into immunocompetent t cells