Lymphatic System Flashcards

1
Q

How much interstitial fluid does the lymphatic system collect per day?

A

3L

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2
Q

How much interstitial fluid does the lymphatic system collect per day?

A

3L

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3
Q

Where are there no lymphatics?

A

CNS

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4
Q

What is cellulitis?

A

An infection of the deeper layers of the skin and underlying tissue

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5
Q

What is an ulcer?

A

A break in the continuity of the epithelium

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6
Q

What is MALT?

A

Mucosal associated lymphatic tissue

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7
Q

Name some lymphatic nodules

A

Tonsils, peyers patches, appendix

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8
Q

Name some lymphatic organs

A

Lymph nodes, thymus, spleen

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9
Q

Where in the GI system are there lots of lymphatics?

A

Small bowel particularly the ileum

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10
Q

What are peyers patches?

A

Organised lymphoid nodules (aggregations of GALT)

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11
Q

Where can peyers patches be found?

A

In the ileum

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12
Q

What is lymph node flow aided by?

A

Adjacent skeletal muscle
Adjacent arteries
Pressure changes in thorax

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13
Q

Is the liver part of the lymphatic system?

A

No

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14
Q

Where do the afferent lymphatics arrive to in the LN?

A

Convex surface

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15
Q

How to the efferent lymphatics leave the LN?

A

Hilum

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16
Q

How are lymphatic nodules arranged?

A

Germinal centres and outer cortex

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17
Q

Where are follicular dendritic cells found?

A

Germinal centres

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18
Q

What do dendritic cells cause?

A

Proliferation of B cells

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19
Q

Name some professional APCs?

A

B cells and macrophages

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20
Q

What cells mediate inflammation?

A

Macrophages and neutrophils

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21
Q

What mediates the humoral response?

A

B cells - produce antibodies

22
Q

What cell medicates the cell mediated response?

A

T cell

23
Q

Why do LN swell in response to infection?

A

Germinal centres fill with lymphocytes

24
Q

Roles of the spleen

A

Antigen presentation
Activation of b and t cells
Remove old and abnormal RBC and platelets
Retrieval of iron from RBC

25
Q

What is there a risk of post splenectomy?

A

Increased risk of infection by encapsulated bacteria

Increased risk of DVT and PE

26
Q

Where is the thymus found?

A

Superior mediastinum

27
Q

What is the role of the thymus?

A

Thymic cell education

Maturation of bone marrow derived stem cells into immunocompetent t cells

28
Q

Where are there no lymphatics?

A

CNS

29
Q

What is cellulitis?

A

An infection of the deeper layers of the skin and underlying tissue

30
Q

What is an ulcer?

A

A break in the continuity of the epithelium

31
Q

What is MALT?

A

Mucosal associated lymphatic tissue

32
Q

Name some lymphatic nodules

A

Tonsils, peyers patches, appendix

33
Q

Name some lymphatic organs

A

Lymph nodes, thymus, spleen

34
Q

Where in the GI system are there lots of lymphatics?

A

Small bowel particularly the ileum

35
Q

What are peyers patches?

A

Organised lymphoid nodules (aggregations of GALT)

36
Q

Where can peyers patches be found?

A

In the ileum

37
Q

What is lymph node flow aided by?

A

Adjacent skeletal muscle
Adjacent arteries
Pressure changes in thorax

38
Q

Is the liver part of the lymphatic system?

A

No

39
Q

Where do the afferent lymphatics arrive to in the LN?

A

Convex surface

40
Q

How to the efferent lymphatics leave the LN?

A

Hilum

41
Q

How are lymphatic nodules arranged?

A

Germinal centres and outer cortex

42
Q

Where are follicular dendritic cells found?

A

Germinal centres

43
Q

What do dendritic cells cause?

A

Proliferation of B cells

44
Q

Name some professional APCs?

A

B cells and macrophages

45
Q

What cells mediate inflammation?

A

Macrophages and neutrophils

46
Q

What mediates the humoral response?

A

B cells - produce antibodies

47
Q

What cell medicates the cell mediated response?

A

T cell

48
Q

Why do LN swell in response to infection?

A

Germinal centres fill with lymphocytes

49
Q

Roles of the spleen

A

Antigen presentation
Activation of b and t cells
Remove old and abnormal RBC and platelets
Retrieval of iron from RBC

50
Q

What is there a risk of post splenectomy?

A

Increased risk of infection by encapsulated bacteria

Increased risk of DVT and PE

51
Q

Where is the thymus found?

A

Superior mediastinum

52
Q

What is the role of the thymus?

A

Thymic cell education

Maturation of bone marrow derived stem cells into immunocompetent t cells