Connective And Adipose Tissue Flashcards

1
Q

What does general Ct contain?

A

cells, fibres and ground substance

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2
Q

Name some fibres in CT

A

Collagen, reticular, elastin

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3
Q

What are the properties of collagen?

A

Flexible with high tensile strength

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4
Q

What is ground substance made of?

A

Proteoglycans (protein +GAG)

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5
Q

What is the role of GAGs?

A

Attract water to make a hydrated gel

Rapid diffusion and resists compression

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6
Q

What is ECM made of?

A

ground substance and fibres

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7
Q

Name the types of CT

A

Dense (regular, irregular), Loose

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8
Q

What type of CT has lots of collagen?

A

Dense

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9
Q

Where would you find loose CT?

A

Beneath epithelia to facilitate diffusion

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10
Q

What do tendons attach?

A

Muscle to bone

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11
Q

What to ligaments attach?

A

Bone to bone

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12
Q

What is an aponeurosis?

A

Flat sheet of regular CT

Adjacent layers arranges at 90 degrees to one another

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13
Q

Advantage of irregular dense CT

A

Can resist forces in multiple directions

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14
Q

Name some fixed cells in CT

A

Fibroblasts, melanocytes, mast cells, macrophage, adipose

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15
Q

Name some wandering cells

A

Monocyte, basophil, leukocyte, plasma cell, eosinophil

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16
Q

What do fibroblasts do?

A

Make ground substance

17
Q

What do myofibroblasts do?

A

Stimulate wound contraction

18
Q

What to mars cell granules contain?

A

Histamine to increase vascular permeability
Heparin
Substances to attract eosinophils and neutrophils

19
Q

Where are mast cells absent?

A

CNS

20
Q

What disease is cause by abnormal collagen 1?

A

Osteogenesis imperfecta

21
Q

What is another name for type 3 collagen?

A

Reticulin

22
Q

Where is type 4 collagen

A

Basement membrane

23
Q

What cell secretes pro collagen?

A

Fibroblast

24
Q

What is vitamin C required for?

A

Intracellular production of pro collagen

25
Q

Where can reticular fibres be found?

A

Lymph nodes

26
Q

What causes Marfans syndrome

A

Abnormal expression of fibrin gene causes abnormal elastic tissue

27
Q

What are the roles of white adipose cells?

A

Fuel reserve
Thermal insulation
Shock absorber

28
Q

Describe the structure of a white fat cell

A

Single fat droplet with nucleus at periphery

29
Q

Describe the structure of a brown fat cell?

A

Many lipid droplets with a central nucleus

30
Q

Why are brown fat cells brown?

A

Rich vascular supply and lots of mitochondria

31
Q

What process can brown fat cells perform?

A

Non shivering thermogenesis

32
Q

What is ghrelin?

A

Appetite stimulator from stomach

33
Q

What is leptin?

A

Appetite suppressor released from fat cells