Connective And Adipose Tissue Flashcards
What does general Ct contain?
cells, fibres and ground substance
Name some fibres in CT
Collagen, reticular, elastin
What are the properties of collagen?
Flexible with high tensile strength
What is ground substance made of?
Proteoglycans (protein +GAG)
What is the role of GAGs?
Attract water to make a hydrated gel
Rapid diffusion and resists compression
What is ECM made of?
ground substance and fibres
Name the types of CT
Dense (regular, irregular), Loose
What type of CT has lots of collagen?
Dense
Where would you find loose CT?
Beneath epithelia to facilitate diffusion
What do tendons attach?
Muscle to bone
What to ligaments attach?
Bone to bone
What is an aponeurosis?
Flat sheet of regular CT
Adjacent layers arranges at 90 degrees to one another
Advantage of irregular dense CT
Can resist forces in multiple directions
Name some fixed cells in CT
Fibroblasts, melanocytes, mast cells, macrophage, adipose
Name some wandering cells
Monocyte, basophil, leukocyte, plasma cell, eosinophil
What do fibroblasts do?
Make ground substance
What do myofibroblasts do?
Stimulate wound contraction
What to mars cell granules contain?
Histamine to increase vascular permeability
Heparin
Substances to attract eosinophils and neutrophils
Where are mast cells absent?
CNS
What disease is cause by abnormal collagen 1?
Osteogenesis imperfecta
What is another name for type 3 collagen?
Reticulin
Where is type 4 collagen
Basement membrane
What cell secretes pro collagen?
Fibroblast
What is vitamin C required for?
Intracellular production of pro collagen
Where can reticular fibres be found?
Lymph nodes
What causes Marfans syndrome
Abnormal expression of fibrin gene causes abnormal elastic tissue
What are the roles of white adipose cells?
Fuel reserve
Thermal insulation
Shock absorber
Describe the structure of a white fat cell
Single fat droplet with nucleus at periphery
Describe the structure of a brown fat cell?
Many lipid droplets with a central nucleus
Why are brown fat cells brown?
Rich vascular supply and lots of mitochondria
What process can brown fat cells perform?
Non shivering thermogenesis
What is ghrelin?
Appetite stimulator from stomach
What is leptin?
Appetite suppressor released from fat cells