Lymphatic System

Question 1

How does fluid flow through lymphatic system

Answer 1

Reliant on muscle contraction, pressure changes and gravity - unidirectional due to valves

Question 2

Describe organisation of system

Answer 2

Blind-end sacs in tissue which are highly permeable, to lymph capillaries which merge to form lymphatic vessels which then join to form lymphatic trunks

Question 3

Role of afferent lymph vessel

Answer 3

Lymph taken from ISF in tissue to lymph node

Question 4

Role of efferent lymph vessel

Answer 4

Lymph node filtration and B cells form antibodies which join lymph fluid

Question 5

Location of lymph node

Answer 5

Cervical 
Axillary 
Tracheobronchial - bifurcation of trachea  
Inguinal 
Abdominal

Question 6

Role of germinal centres (in follicles) during infection?

Answer 6

Rapid B cell formation

Question 7

What does the inner cortex contain?

Answer 7

T cells and dendritic cells that bring information about infection

Question 8

Function of lymph node

Answer 8

Filter lymph and produce an immune response

Question 9

What is the sentinel lymph node?

Answer 9

The FIRST lymph node that tumour spreads to as it drains a cancer

Question 10

Where the the thoracic duct located?

Answer 10

L1 as the cisterns chyli - between the azygous vein and the descending aorta

Drains into the junction of the upper left jugular and left subclavian vein